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FDA Approves Pill Version of Wegovy

FDA Approves Pill Version of Wegovy

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The US Food and Drug Administration today approved a pill version of the blockbuster anti-obesity drug Wegovy. Made by Novo Nordisk, the pill is taken once a day. The company’s original version of Wegovy is a weekly injection. Both drugs contain the same active ingredient, semaglutide.

“This allows patients with obesity who want to lose weight to have a choice between a once weekly injection or a daily tablet,” says Martin Holst Lange, chief scientific officer at Novo Nordisk.

With the soaring popularity of injectable GLP-1 drugs for weight loss, Novo Nordisk and other pharmaceutical companies have been racing to make effective pill versions that could be preferable for some patients. These drugs mimic a naturally occurring hormone in the body that acts on the brain and gut to promote a feeling of fullness.

In clinical trial results published in the New England Journal of Medicine, participants who took the pill achieved an average weight loss of 13.6 percent by 64 weeks. Nearly 30 percent of people lost 20 percent or more of their weight. The study also showed improvements in cardiovascular disease risk and physical activity levels similar to the injectable version.

While pills can sometimes be a more convenient option, patients may not always take them as prescribed, making them less effective. The clinical trial investigators estimated that in an ideal scenario where participants take the pill every day as prescribed, weight loss would be 16.6 percent—which is similar to results seen with injectable Wegovy.

Novo Nordisk first won approval for an oral semaglutide, sold under the brand name Rybelsus, in 2019 to treat type 2 diabetes. That drug has never been approved for obesity and is not as effective for weight loss as newer GLP-1 medications. The Wegovy pill is essentially a higher-dose version of Rybselsus.

“The efficacy for the obesity pill at the end of the day is driven by dose. Higher doses are required to achieve full weight-loss potential for obesity,” Lange says. The Wegovy pill is 25 milligrams while Rybelsus is 14 milligrams.

The most common side effects of oral Wegovy include nausea and vomiting, which are also side effects of the injectable version.

Novo has not disclosed the exact timeline for the drug’s launch, but Lange says it will be available sometime in the first few months of 2026. Production of the medication is already underway at Novo Nordisk’s US manufacturing sites, and the company expects to have enough of the drug to meet US demand.

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You know those little ADT security signs? You know, the ADT logo-emblazoned yard signs or stickers you find in front of houses or slapped on a window by the front door. Well, ADT is rethinking them: today, the home security company announced the ADT Live Light, a light-up version of its logo yard sign that will—you guessed it—shine when your ADT alarm system has been tripped. 

Besides being a visual indicator for your neighbors that something is amiss, ADT says the Live Light could be useful in helping first responders identify which house is yours. It would also serve the same purpose as the stickers and yard signs that came before it: letting would-be intruders know that they risk triggering an alarm by messing with your stuff. And while it can activate automatically, you can also turn it on using the ADT+ app if you want.

The Live Light is wireless and powered by three included AAA lithium batteries. It’s IP65-rated, meaning it should be dust-proof and resistant to water jets from any direction, and should operate in temperatures ranging from 4 to 122 degrees Fahrenheit. Both good things if you’re expecting people to leave their light-up sign out in the elements year-round (although those of us in the Midwest might want to bring it in for a couple of months in the winter). The sign itself is 10 x 10 inches tall and 1.75 inches thick, and goes into the ground with a 21-inch stake, although it can also be wall-mounted. 

The Live Light requires a $25-per-month ADT Professional Monitoring subscription and costs $50, including professional installation. There’s no option to install it yourself; ADT requires that one of its own installers carry out what doesn’t strike me as a terribly complicated procedure. (But what do I know? I’m just a little ol’ country technology reporter.)

Images showing the ADT My Safety feature in the ADT+ app.
© ADT

ADT also announced a new ADT+ app feature called My Safety. My Safety extends ADT’s subscriber service beyond your house by letting you do things like set a check-in timer that, if missed, will prompt ADT to contact emergency services for you. It also offers the manual options of speaking or texting with ADT agents, or setting an “Emergency Phrase” that lets you speak a custom phrase to summon help—that is, ADT will again contact emergency services for you. The company says subscribers will be able to use that last feature even if their phone isn’t in their hand, and I’ve asked exactly how that works.

For the My Safety feature, there’s no call history, and for subscriptions with multiple people on them, only the person who initiates a call with ADT monitoring will be able to see status, activity, alerts, and notifications. It’s nice to see the company has thought of that—it can be important for victims of abuse to be able to discreetly seek help. An ADT representative told Gizmodo via email that the ADT+ app update with My Safety is available now for all subscribers in the U.S., except in Milwaukee, WI.

#ADTs #Big #Idea #LightUp #ADT #Sign #YardADT,apps,Home security,Smart Home">ADT’s New Big Idea Is a Light-Up ADT Sign for Your Yard You know those little ADT security signs? You know, the ADT logo-emblazoned yard signs or stickers you find in front of houses or slapped on a window by the front door. Well, ADT is rethinking them: today, the home security company announced the ADT Live Light, a light-up version of its logo yard sign that will—you guessed it—shine when your ADT alarm system has been tripped.  Besides being a visual indicator for your neighbors that something is amiss, ADT says the Live Light could be useful in helping first responders identify which house is yours. It would also serve the same purpose as the stickers and yard signs that came before it: letting would-be intruders know that they risk triggering an alarm by messing with your stuff. And while it can activate automatically, you can also turn it on using the ADT+ app if you want. © ADT © ADT The Live Light is wireless and powered by three included AAA lithium batteries. It’s IP65-rated, meaning it should be dust-proof and resistant to water jets from any direction, and should operate in temperatures ranging from 4 to 122 degrees Fahrenheit. Both good things if you’re expecting people to leave their light-up sign out in the elements year-round (although those of us in the Midwest might want to bring it in for a couple of months in the winter). The sign itself is 10 x 10 inches tall and 1.75 inches thick, and goes into the ground with a 21-inch stake, although it can also be wall-mounted.  The Live Light requires a -per-month ADT Professional Monitoring subscription and costs , including professional installation. There’s no option to install it yourself; ADT requires that one of its own installers carry out what doesn’t strike me as a terribly complicated procedure. (But what do I know? I’m just a little ol’ country technology reporter.) © ADT ADT also announced a new ADT+ app feature called My Safety. My Safety extends ADT’s subscriber service beyond your house by letting you do things like set a check-in timer that, if missed, will prompt ADT to contact emergency services for you. It also offers the manual options of speaking or texting with ADT agents, or setting an “Emergency Phrase” that lets you speak a custom phrase to summon help—that is, ADT will again contact emergency services for you. The company says subscribers will be able to use that last feature even if their phone isn’t in their hand, and I’ve asked exactly how that works. For the My Safety feature, there’s no call history, and for subscriptions with multiple people on them, only the person who initiates a call with ADT monitoring will be able to see status, activity, alerts, and notifications. It’s nice to see the company has thought of that—it can be important for victims of abuse to be able to discreetly seek help. An ADT representative told Gizmodo via email that the ADT+ app update with My Safety is available now for all subscribers in the U.S., except in Milwaukee, WI. #ADTs #Big #Idea #LightUp #ADT #Sign #YardADT,apps,Home security,Smart Home

ADT Live Light, a light-up version of its logo yard sign that will—you guessed it—shine when your ADT alarm system has been tripped. 

Besides being a visual indicator for your neighbors that something is amiss, ADT says the Live Light could be useful in helping first responders identify which house is yours. It would also serve the same purpose as the stickers and yard signs that came before it: letting would-be intruders know that they risk triggering an alarm by messing with your stuff. And while it can activate automatically, you can also turn it on using the ADT+ app if you want.

The Live Light is wireless and powered by three included AAA lithium batteries. It’s IP65-rated, meaning it should be dust-proof and resistant to water jets from any direction, and should operate in temperatures ranging from 4 to 122 degrees Fahrenheit. Both good things if you’re expecting people to leave their light-up sign out in the elements year-round (although those of us in the Midwest might want to bring it in for a couple of months in the winter). The sign itself is 10 x 10 inches tall and 1.75 inches thick, and goes into the ground with a 21-inch stake, although it can also be wall-mounted. 

The Live Light requires a $25-per-month ADT Professional Monitoring subscription and costs $50, including professional installation. There’s no option to install it yourself; ADT requires that one of its own installers carry out what doesn’t strike me as a terribly complicated procedure. (But what do I know? I’m just a little ol’ country technology reporter.)

Images showing the ADT My Safety feature in the ADT+ app.
© ADT

ADT also announced a new ADT+ app feature called My Safety. My Safety extends ADT’s subscriber service beyond your house by letting you do things like set a check-in timer that, if missed, will prompt ADT to contact emergency services for you. It also offers the manual options of speaking or texting with ADT agents, or setting an “Emergency Phrase” that lets you speak a custom phrase to summon help—that is, ADT will again contact emergency services for you. The company says subscribers will be able to use that last feature even if their phone isn’t in their hand, and I’ve asked exactly how that works.

For the My Safety feature, there’s no call history, and for subscriptions with multiple people on them, only the person who initiates a call with ADT monitoring will be able to see status, activity, alerts, and notifications. It’s nice to see the company has thought of that—it can be important for victims of abuse to be able to discreetly seek help. An ADT representative told Gizmodo via email that the ADT+ app update with My Safety is available now for all subscribers in the U.S., except in Milwaukee, WI.

#ADTs #Big #Idea #LightUp #ADT #Sign #YardADT,apps,Home security,Smart Home">ADT’s New Big Idea Is a Light-Up ADT Sign for Your Yard

You know those little ADT security signs? You know, the ADT logo-emblazoned yard signs or stickers you find in front of houses or slapped on a window by the front door. Well, ADT is rethinking them: today, the home security company announced the ADT Live Light, a light-up version of its logo yard sign that will—you guessed it—shine when your ADT alarm system has been tripped. 

Besides being a visual indicator for your neighbors that something is amiss, ADT says the Live Light could be useful in helping first responders identify which house is yours. It would also serve the same purpose as the stickers and yard signs that came before it: letting would-be intruders know that they risk triggering an alarm by messing with your stuff. And while it can activate automatically, you can also turn it on using the ADT+ app if you want.

The Live Light is wireless and powered by three included AAA lithium batteries. It’s IP65-rated, meaning it should be dust-proof and resistant to water jets from any direction, and should operate in temperatures ranging from 4 to 122 degrees Fahrenheit. Both good things if you’re expecting people to leave their light-up sign out in the elements year-round (although those of us in the Midwest might want to bring it in for a couple of months in the winter). The sign itself is 10 x 10 inches tall and 1.75 inches thick, and goes into the ground with a 21-inch stake, although it can also be wall-mounted. 

The Live Light requires a $25-per-month ADT Professional Monitoring subscription and costs $50, including professional installation. There’s no option to install it yourself; ADT requires that one of its own installers carry out what doesn’t strike me as a terribly complicated procedure. (But what do I know? I’m just a little ol’ country technology reporter.)

Images showing the ADT My Safety feature in the ADT+ app.
© ADT

ADT also announced a new ADT+ app feature called My Safety. My Safety extends ADT’s subscriber service beyond your house by letting you do things like set a check-in timer that, if missed, will prompt ADT to contact emergency services for you. It also offers the manual options of speaking or texting with ADT agents, or setting an “Emergency Phrase” that lets you speak a custom phrase to summon help—that is, ADT will again contact emergency services for you. The company says subscribers will be able to use that last feature even if their phone isn’t in their hand, and I’ve asked exactly how that works.

For the My Safety feature, there’s no call history, and for subscriptions with multiple people on them, only the person who initiates a call with ADT monitoring will be able to see status, activity, alerts, and notifications. It’s nice to see the company has thought of that—it can be important for victims of abuse to be able to discreetly seek help. An ADT representative told Gizmodo via email that the ADT+ app update with My Safety is available now for all subscribers in the U.S., except in Milwaukee, WI.

#ADTs #Big #Idea #LightUp #ADT #Sign #YardADT,apps,Home security,Smart Home

TL;DR: Score a free iPhone 17e when signing up for a T-Mobile plan with no trade-in required. Alternatively, you can get the iPhone 17 for free from T-Mobile when signing up for an Experience More plan and trading in an eligible device.

In the mobile world, the word “free” is usually followed by a list of caveats that make you wish you never started looking for a deal. You usually need to sign up for the most expensive plan or trade-in a premium phone to get your hands on what you really want. But that’s not the case with the latest T-Mobile offer.

T-Mobile is offering a rare deal on the newly-released Apple iPhone 17e. For a limited time, you can pick up this A19-powered device for free by simply opening a new line.

You’ll need to activate a new line on T-Mobile’s Experience Beyond or Experience More plans to get the iPhone 17e for free. The phone’s full retail price is covered via 24 monthly bill credits, and since you aren’t trading in your old phone, you can keep it as a backup, give it to a kid, or sell it on a third-party site to actually make money on this deal.

Mashable’s Stan Shroeder got his hands on the iPhone 17e and said “The combination of having Apple’s latest chip and a decent amount of storage means this phone will be relevant for at least four to five years.” That’s an impressive lifespan for a budget-friendly phone, particularly when it’s free.

SEE ALSO: Apple’s iPhone Fold launch might happen later than we thought (updated)

If you need something a little more powerful, you can also pick up the iPhone 17 for free from T-Mobile when signing on for 24 months of an Experience More plan and trading in an eligible phone. That gets you unthrottled 5G data, 4K streaming, and enough international roaming for even the most adventurous of travellers.

It’s important to note that T-Mobile will charge taxes on these free deals and a $35 device connection fee. Is this really “free” when you need to sign up to something or pay an upfront fee? It’s a gray area — we’re doing our best, OK?

Score an iPhone 17 for free this week with T-Mobile.

#TMobile #giving #Apple #iPhone #free #claim">T-Mobile is giving away the Apple iPhone 17 for free — how to claim TL;DR: Score a free iPhone 17e when signing up for a T-Mobile plan with no trade-in required. Alternatively, you can get the iPhone 17 for free from T-Mobile when signing up for an Experience More plan and trading in an eligible device. In the mobile world, the word “free” is usually followed by a list of caveats that make you wish you never started looking for a deal. You usually need to sign up for the most expensive plan or trade-in a premium phone to get your hands on what you really want. But that’s not the case with the latest T-Mobile offer.T-Mobile is offering a rare deal on the newly-released Apple iPhone 17e. For a limited time, you can pick up this A19-powered device for free by simply opening a new line. You’ll need to activate a new line on T-Mobile’s Experience Beyond or Experience More plans to get the iPhone 17e for free. The phone’s full retail price is covered via 24 monthly bill credits, and since you aren’t trading in your old phone, you can keep it as a backup, give it to a kid, or sell it on a third-party site to actually make money on this deal. Mashable’s Stan Shroeder got his hands on the iPhone 17e and said “The combination of having Apple’s latest chip and a decent amount of storage means this phone will be relevant for at least four to five years.” That’s an impressive lifespan for a budget-friendly phone, particularly when it’s free. SEE ALSO: Apple’s iPhone Fold launch might happen later than we thought (updated) If you need something a little more powerful, you can also pick up the iPhone 17 for free from T-Mobile when signing on for 24 months of an Experience More plan and trading in an eligible phone. That gets you unthrottled 5G data, 4K streaming, and enough international roaming for even the most adventurous of travellers. Mashable Deals By signing up, you agree to receive recurring automated SMS marketing messages from Mashable Deals at the number provided. Msg and data rates may apply. Up to 2 messages/day. Reply STOP to opt out, HELP for help. Consent is not a condition of purchase. See our Privacy Policy and Terms of Use. It’s important to note that T-Mobile will charge taxes on these free deals and a device connection fee. Is this really “free” when you need to sign up to something or pay an upfront fee? It’s a gray area — we’re doing our best, OK?Score an iPhone 17 for free this week with T-Mobile. #TMobile #giving #Apple #iPhone #free #claim

free iPhone 17e when signing up for a T-Mobile plan with no trade-in required. Alternatively, you can get the iPhone 17 for free from T-Mobile when signing up for an Experience More plan and trading in an eligible device.

In the mobile world, the word “free” is usually followed by a list of caveats that make you wish you never started looking for a deal. You usually need to sign up for the most expensive plan or trade-in a premium phone to get your hands on what you really want. But that’s not the case with the latest T-Mobile offer.

T-Mobile is offering a rare deal on the newly-released Apple iPhone 17e. For a limited time, you can pick up this A19-powered device for free by simply opening a new line.

You’ll need to activate a new line on T-Mobile’s Experience Beyond or Experience More plans to get the iPhone 17e for free. The phone’s full retail price is covered via 24 monthly bill credits, and since you aren’t trading in your old phone, you can keep it as a backup, give it to a kid, or sell it on a third-party site to actually make money on this deal.

Mashable’s Stan Shroeder got his hands on the iPhone 17e and said “The combination of having Apple’s latest chip and a decent amount of storage means this phone will be relevant for at least four to five years.” That’s an impressive lifespan for a budget-friendly phone, particularly when it’s free.

SEE ALSO: Apple’s iPhone Fold launch might happen later than we thought (updated)

If you need something a little more powerful, you can also pick up the iPhone 17 for free from T-Mobile when signing on for 24 months of an Experience More plan and trading in an eligible phone. That gets you unthrottled 5G data, 4K streaming, and enough international roaming for even the most adventurous of travellers.

It’s important to note that T-Mobile will charge taxes on these free deals and a $35 device connection fee. Is this really “free” when you need to sign up to something or pay an upfront fee? It’s a gray area — we’re doing our best, OK?

Score an iPhone 17 for free this week with T-Mobile.

#TMobile #giving #Apple #iPhone #free #claim">T-Mobile is giving away the Apple iPhone 17 for free — how to claim

TL;DR: Score a free iPhone 17e when signing up for a T-Mobile plan with no trade-in required. Alternatively, you can get the iPhone 17 for free from T-Mobile when signing up for an Experience More plan and trading in an eligible device.

In the mobile world, the word “free” is usually followed by a list of caveats that make you wish you never started looking for a deal. You usually need to sign up for the most expensive plan or trade-in a premium phone to get your hands on what you really want. But that’s not the case with the latest T-Mobile offer.

T-Mobile is offering a rare deal on the newly-released Apple iPhone 17e. For a limited time, you can pick up this A19-powered device for free by simply opening a new line.

You’ll need to activate a new line on T-Mobile’s Experience Beyond or Experience More plans to get the iPhone 17e for free. The phone’s full retail price is covered via 24 monthly bill credits, and since you aren’t trading in your old phone, you can keep it as a backup, give it to a kid, or sell it on a third-party site to actually make money on this deal.

Mashable’s Stan Shroeder got his hands on the iPhone 17e and said “The combination of having Apple’s latest chip and a decent amount of storage means this phone will be relevant for at least four to five years.” That’s an impressive lifespan for a budget-friendly phone, particularly when it’s free.

SEE ALSO: Apple’s iPhone Fold launch might happen later than we thought (updated)

If you need something a little more powerful, you can also pick up the iPhone 17 for free from T-Mobile when signing on for 24 months of an Experience More plan and trading in an eligible phone. That gets you unthrottled 5G data, 4K streaming, and enough international roaming for even the most adventurous of travellers.

It’s important to note that T-Mobile will charge taxes on these free deals and a $35 device connection fee. Is this really “free” when you need to sign up to something or pay an upfront fee? It’s a gray area — we’re doing our best, OK?

Score an iPhone 17 for free this week with T-Mobile.

#TMobile #giving #Apple #iPhone #free #claim

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