Nucleus Genomics, a genetic testing startup founded by 25-year-old Kian Sadeghi, initially launched in 2021 with the goal of calculating a patient’s risk for specific diseases.
But it’s been courting controversy for years with products that claim to tell people how their genetics correlate to a host of complex issues, including their IQ.
On Wednesday, it ratcheted up the controversy to an ear-splitting level when it announced a new product called Nucleus Embryo with a tweet that said: “Every parent wants to give their children more than they had. For the first time in human history, Nucleus adds a new tool to that commitment.”
Nucleus says it can test IVF embryos not just for well-known specific genes that have a high chance of illnesses like breast cancer, but also for appearance — sex, height, hair color, eye color — as well as IQ and complex health attributes like anxiety and ADHD.
The launch video includes a screen shot of a comparison menu. The idea is to help parents choose which embryos to pick and which ones to, perhaps, discard.
Genetic testing of embryos isn’t unheard of. IVF physicians can test for genes that can cause conditions like Down syndrome, or when parents know they are of high risk for a particular genetic disorder, like cystic fibrosis.
But that’s not exactly what Nucleus is doing. It is using controversial “polygenic scores” to determine “complex genetic outcomes, like intelligence and anxiety,” a spokesperson says.
According to the National Human Genome Research Institute, polygenic scores only calculate the probabilities of a certain complex illness occurring, mainly within populations. “A polygenic risk score can only explain the relative risk for a disease,” the NHGR says. This is not the same as discovering a specific gene, such as for example the BRCA1 gene mutation, which gives a person a 60-80% “absolute risk of breast cancer,” the NHGR says.
There’s a reason doctors don’t typically use such tests for individuals. “Polygenic risk scores are not yet routinely used by health professionals because there are no guidelines for practice and researchers are still improving how these scores are generated,” according to the NHGR.
Nucleus defends that its method can be used to determine an individual’s risk. The spokesperson pointed us to a 2018 paper where the authors said they had developed validated methods for five common diseases: coronary artery disease, atrial fibrillation, type 2 diabetes, inflammatory bowel disease, and breast cancer.
That paper was advocating screenings to help individuals make lifestyle or therapeutic decisions, similar to Nucleus’s initial concept.
Wednesday’s tweet was promising parents that Nucleus can help them create designer babies. It has now been viewed more than 4 million times and has hundreds of comments, many of them either expressing disbelief that this works as promised, or horror at the idea.
One VC chimed into the discussion saying, “I was going to type something like Noah get the boat but honestly the reality of this just makes me so nauseous.”
Nucleus has experienced this kind of controversy before, as TechCrunch previously reported, when it its $14 million series A earlier this year. The startup is backed by Founders Fund, Alexis Ohanian’s 776, and angels including Adrian Aoun (CEO at Forward Health), Brent Saunders (former CEO at Allergan), and Matteo Franceschetti (CEO at Eight Sleep).
Last year, Sadeghi launched Nucleus IQ, which is supposed to tell users how much their genetics influence intelligence. The product was blasted as “bad science and big business” by some critics. Sadeghi published a lengthy defense of his company’s methodology.
Even so, telling adults that they are genetically smart is one thing. Telling IVF parents that they can choose the appearance and other complex attributes for their children is, many would argue, something else.
Nucleus is not currently conducting such tests via IVF lab partners itself, The Wall Street Journal reports. It’s partnering with Genomic Prediction, which works with IVF clinics. A Genomic executive told the WSJ that many parents request intelligence tests, and it doesn’t provide that. Parents can voluntarily upload genetic data information to Nucleas if they want to pursue it.
Or, as Sadeghi said in the launch video aimed at would-be parents: “Not that long ago IVF-1 sparked fear and the stigma of test tube babies,” he said. “What was once controversial is now an everyday practice. The same is true with genetic optimization. The technology is now here and it’s here to stay.”
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#Genetics #testing #startup #Nucleus #Genomics #criticized #embryo #product #nauseous
![Palantir Debuts Chic Chore Coat So the World Knows You’re One of the Baddies
This week, Palantir announced the upcoming release of a new chore coat branded with the company’s logo. The company has been releasing gear since 2024, and this new coat is a great way to tell everyone what you stand for. Specifically, it communicates to everyone in your immediate vicinity that you support ICE and aren’t a big fan of civil liberties. Palantir’s head of strategic engagement Eliano A. Younes tweeted the chore coat this week, which he says will be released on April 30. the lightweight Palantir chore coat [04.30.2026 • 0930 AM EST] pic.twitter.com/9K5fmu3bSs — Eliano A Younes (@eliano) April 21, 2026 X users responded to Younes with the kind of comments that anyone might expect about Palantir, a company aligned with President Donald Trump and the most dystopian elements of our modern surveillance society.
“could it be operated remotely ? detonated? listening ? what’s the features list,” one user joked, while another asked if it had “built in surveillance trackers?” But Younes seemed genuinely offended by the most obvious jokes any reasonable person might be expected to make of Palantir, a defense contractor that prides itself in helping surveil and kill people around the world. He responded with “here for the shitposting but I need to see better from you. this is unoriginal and not funny,” and “not even remotely funny. try harder.”
Even Palantir employees seem to be waking up to what the company stands for, according to a recent report from Wired. When the U.S. launched a missile attack against an elementary school in Iran on Feb. 28 that killed about 175 people, mostly children, the employees reportedly started to question whether Palantir’s Maven technology had been used. Employees are also worried about the company’s lucrative contracts with ICE, an organization that has been terrorizing American streets in particularly heinous ways.
But Palantir seems intent on pushing out gear that allows like-minded people to wrap themselves in a horrifying, anti-American brand. “We want millions of people wearing Palantir merch around the world,” recently Younes told GQ. Younes says he wants Palantir to be a lifestyle brand, telling GQ, “There are people out there wearing Palantir merchandise to signal their alignment with our mission, and that’s exactly what a lifestyle brand is.” That lifestyle, of course, isn’t something that decent people would be proud of. Palantir recently promoted a Reader’s Digest-style version of the book The Technological Republic, co-authored by CEO Alex Karp, in a tweet. The book advocates for reinstatement of the draft, says the “postwar neutering” of Germany and Japan following the atrocities of World War II was an overcorrection, and criticizes the concept of pluralism.
It’s not just the chore coat. The company also sell sweatshirts, t-shirts, and hats, among other items. One t-shirt Palantir sold in 2025 featured an image of Karp along with the word “Dominate.” That item is no longer available for purchase. Younes also suggested to GQ that its CEO was important for Palantir as a fashion brand: “A lot of the store’s designs are downstream of Dr. Karp and our chief technology officer Shyam Sankar’s personal style.” Younes wouldn’t say how many units the company is selling, but did claim, “store sales have increased 64% year-over-year and everything we’ve made has sold out, sometimes in minutes.”
GQ asked about Palantir’s ICE contracts and the other “controversial” things it’s engaged in with the U.S. military, but Younes insisted the company is “not political,” whatever that’s supposed to mean. As the Wall Street Journal recently pointed out, Palantir is leaning hard into selling the “tech-boss-as-hero ethos,” that’s frankly pretty common in Silicon Valley these days. But even some fans of the company think the merchandising effort is embarrassing.
“Unpopular opinion: all these merch posts are so ‘fan boy’ and extra cringe,” one user wrote in the Palantir subreddit about Karp’s Dominate shirt. “Like the stock or don’t, believe in the company or don’t,…. But the incessant merch posts are weak sauce.” Others are fully bought in, with one user writing, “Definitely a collectors item for me, could be worth something one day.” Younes told GQ that Palantir is working on a tennis collection and something for the America 250 celebrations this summer. So if you’re a fan of techno-fascism, keep your eyes peeled. Whatever merch they’ve got planned for the rest of the year could be sold out in no time. #Palantir #Debuts #Chic #Chore #Coat #World #Youre #BaddiesPalantir](https://i1.wp.com/gizmodo.com/app/uploads/2026/04/palatnir-chore-coats-1280x853.jpg?ssl=1 "Palantir Debuts Chic Chore Coat So the World Knows You’re One of the Baddies
This week, Palantir announced the upcoming release of a new chore coat branded with the company’s logo. The company has been releasing gear since 2024, and this new coat is a great way to tell everyone what you stand for. Specifically, it communicates to everyone in your immediate vicinity that you support ICE and aren’t a big fan of civil liberties. Palantir’s head of strategic engagement Eliano A. Younes tweeted the chore coat this week, which he says will be released on April 30. the lightweight Palantir chore coat [04.30.2026 • 0930 AM EST] pic.twitter.com/9K5fmu3bSs — Eliano A Younes (@eliano) April 21, 2026 X users responded to Younes with the kind of comments that anyone might expect about Palantir, a company aligned with President Donald Trump and the most dystopian elements of our modern surveillance society.
“could it be operated remotely ? detonated? listening ? what’s the features list,” one user joked, while another asked if it had “built in surveillance trackers?” But Younes seemed genuinely offended by the most obvious jokes any reasonable person might be expected to make of Palantir, a defense contractor that prides itself in helping surveil and kill people around the world. He responded with “here for the shitposting but I need to see better from you. this is unoriginal and not funny,” and “not even remotely funny. try harder.”
Even Palantir employees seem to be waking up to what the company stands for, according to a recent report from Wired. When the U.S. launched a missile attack against an elementary school in Iran on Feb. 28 that killed about 175 people, mostly children, the employees reportedly started to question whether Palantir’s Maven technology had been used. Employees are also worried about the company’s lucrative contracts with ICE, an organization that has been terrorizing American streets in particularly heinous ways.
But Palantir seems intent on pushing out gear that allows like-minded people to wrap themselves in a horrifying, anti-American brand. “We want millions of people wearing Palantir merch around the world,” recently Younes told GQ. Younes says he wants Palantir to be a lifestyle brand, telling GQ, “There are people out there wearing Palantir merchandise to signal their alignment with our mission, and that’s exactly what a lifestyle brand is.” That lifestyle, of course, isn’t something that decent people would be proud of. Palantir recently promoted a Reader’s Digest-style version of the book The Technological Republic, co-authored by CEO Alex Karp, in a tweet. The book advocates for reinstatement of the draft, says the “postwar neutering” of Germany and Japan following the atrocities of World War II was an overcorrection, and criticizes the concept of pluralism.
It’s not just the chore coat. The company also sell sweatshirts, t-shirts, and hats, among other items. One t-shirt Palantir sold in 2025 featured an image of Karp along with the word “Dominate.” That item is no longer available for purchase. Younes also suggested to GQ that its CEO was important for Palantir as a fashion brand: “A lot of the store’s designs are downstream of Dr. Karp and our chief technology officer Shyam Sankar’s personal style.” Younes wouldn’t say how many units the company is selling, but did claim, “store sales have increased 64% year-over-year and everything we’ve made has sold out, sometimes in minutes.”
GQ asked about Palantir’s ICE contracts and the other “controversial” things it’s engaged in with the U.S. military, but Younes insisted the company is “not political,” whatever that’s supposed to mean. As the Wall Street Journal recently pointed out, Palantir is leaning hard into selling the “tech-boss-as-hero ethos,” that’s frankly pretty common in Silicon Valley these days. But even some fans of the company think the merchandising effort is embarrassing.
“Unpopular opinion: all these merch posts are so ‘fan boy’ and extra cringe,” one user wrote in the Palantir subreddit about Karp’s Dominate shirt. “Like the stock or don’t, believe in the company or don’t,…. But the incessant merch posts are weak sauce.” Others are fully bought in, with one user writing, “Definitely a collectors item for me, could be worth something one day.” Younes told GQ that Palantir is working on a tennis collection and something for the America 250 celebrations this summer. So if you’re a fan of techno-fascism, keep your eyes peeled. Whatever merch they’ve got planned for the rest of the year could be sold out in no time. #Palantir #Debuts #Chic #Chore #Coat #World #Youre #BaddiesPalantir")
![Palantir Debuts Chic Chore Coat So the World Knows You’re One of the Baddies
This week, Palantir announced the upcoming release of a new chore coat branded with the company’s logo. The company has been releasing gear since 2024, and this new coat is a great way to tell everyone what you stand for. Specifically, it communicates to everyone in your immediate vicinity that you support ICE and aren’t a big fan of civil liberties. Palantir’s head of strategic engagement Eliano A. Younes tweeted the chore coat this week, which he says will be released on April 30. the lightweight Palantir chore coat [04.30.2026 • 0930 AM EST] pic.twitter.com/9K5fmu3bSs — Eliano A Younes (@eliano) April 21, 2026 X users responded to Younes with the kind of comments that anyone might expect about Palantir, a company aligned with President Donald Trump and the most dystopian elements of our modern surveillance society.
“could it be operated remotely ? detonated? listening ? what’s the features list,” one user joked, while another asked if it had “built in surveillance trackers?” But Younes seemed genuinely offended by the most obvious jokes any reasonable person might be expected to make of Palantir, a defense contractor that prides itself in helping surveil and kill people around the world. He responded with “here for the shitposting but I need to see better from you. this is unoriginal and not funny,” and “not even remotely funny. try harder.”
Even Palantir employees seem to be waking up to what the company stands for, according to a recent report from Wired. When the U.S. launched a missile attack against an elementary school in Iran on Feb. 28 that killed about 175 people, mostly children, the employees reportedly started to question whether Palantir’s Maven technology had been used. Employees are also worried about the company’s lucrative contracts with ICE, an organization that has been terrorizing American streets in particularly heinous ways.
But Palantir seems intent on pushing out gear that allows like-minded people to wrap themselves in a horrifying, anti-American brand. “We want millions of people wearing Palantir merch around the world,” recently Younes told GQ. Younes says he wants Palantir to be a lifestyle brand, telling GQ, “There are people out there wearing Palantir merchandise to signal their alignment with our mission, and that’s exactly what a lifestyle brand is.” That lifestyle, of course, isn’t something that decent people would be proud of. Palantir recently promoted a Reader’s Digest-style version of the book The Technological Republic, co-authored by CEO Alex Karp, in a tweet. The book advocates for reinstatement of the draft, says the “postwar neutering” of Germany and Japan following the atrocities of World War II was an overcorrection, and criticizes the concept of pluralism.
It’s not just the chore coat. The company also sell sweatshirts, t-shirts, and hats, among other items. One t-shirt Palantir sold in 2025 featured an image of Karp along with the word “Dominate.” That item is no longer available for purchase. Younes also suggested to GQ that its CEO was important for Palantir as a fashion brand: “A lot of the store’s designs are downstream of Dr. Karp and our chief technology officer Shyam Sankar’s personal style.” Younes wouldn’t say how many units the company is selling, but did claim, “store sales have increased 64% year-over-year and everything we’ve made has sold out, sometimes in minutes.”
GQ asked about Palantir’s ICE contracts and the other “controversial” things it’s engaged in with the U.S. military, but Younes insisted the company is “not political,” whatever that’s supposed to mean. As the Wall Street Journal recently pointed out, Palantir is leaning hard into selling the “tech-boss-as-hero ethos,” that’s frankly pretty common in Silicon Valley these days. But even some fans of the company think the merchandising effort is embarrassing.
“Unpopular opinion: all these merch posts are so ‘fan boy’ and extra cringe,” one user wrote in the Palantir subreddit about Karp’s Dominate shirt. “Like the stock or don’t, believe in the company or don’t,…. But the incessant merch posts are weak sauce.” Others are fully bought in, with one user writing, “Definitely a collectors item for me, could be worth something one day.” Younes told GQ that Palantir is working on a tennis collection and something for the America 250 celebrations this summer. So if you’re a fan of techno-fascism, keep your eyes peeled. Whatever merch they’ve got planned for the rest of the year could be sold out in no time. #Palantir #Debuts #Chic #Chore #Coat #World #Youre #BaddiesPalantir](https://gizmodo.com/app/uploads/2026/04/palatnir-chore-coats-1280x853.jpg "Palantir Debuts Chic Chore Coat So the World Knows You’re One of the Baddies
This week, Palantir announced the upcoming release of a new chore coat branded with the company’s logo. The company has been releasing gear since 2024, and this new coat is a great way to tell everyone what you stand for. Specifically, it communicates to everyone in your immediate vicinity that you support ICE and aren’t a big fan of civil liberties. Palantir’s head of strategic engagement Eliano A. Younes tweeted the chore coat this week, which he says will be released on April 30. the lightweight Palantir chore coat [04.30.2026 • 0930 AM EST] pic.twitter.com/9K5fmu3bSs — Eliano A Younes (@eliano) April 21, 2026 X users responded to Younes with the kind of comments that anyone might expect about Palantir, a company aligned with President Donald Trump and the most dystopian elements of our modern surveillance society.
“could it be operated remotely ? detonated? listening ? what’s the features list,” one user joked, while another asked if it had “built in surveillance trackers?” But Younes seemed genuinely offended by the most obvious jokes any reasonable person might be expected to make of Palantir, a defense contractor that prides itself in helping surveil and kill people around the world. He responded with “here for the shitposting but I need to see better from you. this is unoriginal and not funny,” and “not even remotely funny. try harder.”
Even Palantir employees seem to be waking up to what the company stands for, according to a recent report from Wired. When the U.S. launched a missile attack against an elementary school in Iran on Feb. 28 that killed about 175 people, mostly children, the employees reportedly started to question whether Palantir’s Maven technology had been used. Employees are also worried about the company’s lucrative contracts with ICE, an organization that has been terrorizing American streets in particularly heinous ways.
But Palantir seems intent on pushing out gear that allows like-minded people to wrap themselves in a horrifying, anti-American brand. “We want millions of people wearing Palantir merch around the world,” recently Younes told GQ. Younes says he wants Palantir to be a lifestyle brand, telling GQ, “There are people out there wearing Palantir merchandise to signal their alignment with our mission, and that’s exactly what a lifestyle brand is.” That lifestyle, of course, isn’t something that decent people would be proud of. Palantir recently promoted a Reader’s Digest-style version of the book The Technological Republic, co-authored by CEO Alex Karp, in a tweet. The book advocates for reinstatement of the draft, says the “postwar neutering” of Germany and Japan following the atrocities of World War II was an overcorrection, and criticizes the concept of pluralism.
It’s not just the chore coat. The company also sell sweatshirts, t-shirts, and hats, among other items. One t-shirt Palantir sold in 2025 featured an image of Karp along with the word “Dominate.” That item is no longer available for purchase. Younes also suggested to GQ that its CEO was important for Palantir as a fashion brand: “A lot of the store’s designs are downstream of Dr. Karp and our chief technology officer Shyam Sankar’s personal style.” Younes wouldn’t say how many units the company is selling, but did claim, “store sales have increased 64% year-over-year and everything we’ve made has sold out, sometimes in minutes.”
GQ asked about Palantir’s ICE contracts and the other “controversial” things it’s engaged in with the U.S. military, but Younes insisted the company is “not political,” whatever that’s supposed to mean. As the Wall Street Journal recently pointed out, Palantir is leaning hard into selling the “tech-boss-as-hero ethos,” that’s frankly pretty common in Silicon Valley these days. But even some fans of the company think the merchandising effort is embarrassing.
“Unpopular opinion: all these merch posts are so ‘fan boy’ and extra cringe,” one user wrote in the Palantir subreddit about Karp’s Dominate shirt. “Like the stock or don’t, believe in the company or don’t,…. But the incessant merch posts are weak sauce.” Others are fully bought in, with one user writing, “Definitely a collectors item for me, could be worth something one day.” Younes told GQ that Palantir is working on a tennis collection and something for the America 250 celebrations this summer. So if you’re a fan of techno-fascism, keep your eyes peeled. Whatever merch they’ve got planned for the rest of the year could be sold out in no time. #Palantir #Debuts #Chic #Chore #Coat #World #Youre #BaddiesPalantir")
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