When Will Bruey talks about the future, the timelines are shorter than most might imagine. The Varda Space Industries CEO predicts that within 10 years, someone could stand at a landing site and watch multiple specialized spacecraft per night zooming toward Earth like shooting stars, each carrying pharmaceuticals manufactured in space. Within 15 to 20 years, he says, it will be cheaper to send a working-class employee to orbit for a month than to keep them on Earth.
The reason Bruey thinks these scenarios are realistic is because he has watched ambitious business projections unfold before, while working as an engineer at SpaceX.
“I remember the first rocket I worked on at SpaceX was flight three of Falcon 9,” he said at TechCrunch’s recent Disrupt event. The partially reusable, two-stage, medium-lift launch vehicle has since completed nearly 600 successful missions. “If someone had told me ‘reusable rockets,’ and ‘[we’ll see as] many [of these] flights as daily flights out of LAX,’ I would have been like, ‘All right, [maybe in] 15 to 20 years,’ and this feels the same level of futuristic.”
Varda has already proven the core concept. In February 2024, after a months-long regulatory odyssey, the company became only the third corporate entity ever to bring something back from orbit – crystals of ritonavir, an HIV medication – joining SpaceX and Boeing in that exclusive club. It has completed a handful of missions since.
The company brings its pharmaceuticals back to Earth inside the W-1 capsule, a small, conical spacecraft about 90 centimeters across, 74 centimeters high, and weighing less than 90 kilograms (roughly the size of a large kitchen trash can). The company this week launched its fifth capsule ever aboard a SpaceX ride-share mission, hosted by a spacecraft bus that provides power, communications, propulsion, and control while in orbit.
So why manufacture crystals in space? In microgravity, the usual forces that interfere with crystal formation on Earth – like sedimentation and gravity pulling on growing crystals – essentially disappear. Varda says that this gives it much more precise control over crystallization, allowing it to create crystals with uniform sizes or even novel polymorphs (different structural arrangements of the same molecule). These improvements can ostensibly translate into real benefits: better stability, greater purity, and longer shelf life for drugs.
The process isn’t quick. Pharmaceutical manufacturing can take weeks or months in orbit. But once it’s complete, the capsule detaches from the spacecraft bus and plunges back through Earth’s atmosphere at over 30,000 kilometers per hour, reaching speeds above Mach 25. A heat shield made of NASA-developed carbon ablator material protects the cargo inside, and a parachute brings it down for a soft landing.
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The actual business is pretty prosaic, though, Bruey offered. “Forget about space for a second,” he said. “We just have this magic oven . . . where you can create formulations that you otherwise couldn’t.” Added Bruey of what people often get wrong about Varda, the company isn’t “in the space industry; we’re in-space industry,” he said. Space is “just another place to ship to.”
Worth noting: Varda isn’t discovering new drugs or creating new molecules. It’s aiming to expand the menu of what can be done with existing, approved drugs.
This isn’t speculative science, either. Companies like Bristol Myers Squibb and Merck have been running pharmaceutical crystallization experiments on the International Space Station for years, proving the concept works. Varda says it’s just making it commercial by building the infrastructure to do it repeatedly, reliably, and at a scale that might actually matter to the pharmaceutical industry.
As for why now, two things have changed. First, space launches have become bookable and predictable. “Ten years ago, you would have to get a chartered flight. It was like hitchhiking to get to orbit if you were not a primary mission payload,” Bruey explained. “It’s still expensive today, but [it’s dependable, you can book a slot, and we [have] booked launches years in advance.”
Second, end-to-end space service companies like Rocket Lab started producing satellite buses that could be purchased off the shelf. Buying spacecraft from Rocket Lab and integrating its pharmaceutical manufacturing capsules with them is a major unlock.
Still, only the highest-value products make economic sense. That’s why Varda started with pharmaceuticals; a drug that can command thousands of dollars per dose can absorb the transportation costs.
The “seven domino” theory
When Bruey talks to members of Congress, which he says he does frequently these days, he pitches what he calls the “seven domino theory.”
Domino one: reusable rockets. Done. Domino two: manufacturing drugs in orbit and returning them. Domino three is the big one: getting a drug into clinical trials. “It’s a big deal because what it means is perpetual launch.”
This is where Varda’s business model diverges fundamentally from every other space company.
Think about how satellite companies work. SiriusXM launches satellites to broadcast radio. DirecTV launches satellites to transmit television. Even Starlink, with its thousands of satellites, is fundamentally building out a constellation – a network that, once complete, doesn’t require constant launches to function. These companies treat launch as a capital investment. They spend money to place hardware in orbit, and then they’re done.
Varda is different. Each drug formulation requires manufacturing runs. Manufacturing runs require launches. More demand for the drugs means more launches.
This matters because it changes the economics for launch providers. Instead of selling a fixed number of launches to build out a constellation, they have a customer with (theoretically) unlimited demand that grows with success. That kind of predictable, scalable demand helps justify the fixed costs of launch infrastructure and drives down per-launch prices.
Domino four triggers the feedback loop: as Varda scales, costs drop, making the next tier of drugs economically viable. More drugs mean more scale, lowering costs again – a cycle Bruey says will “shove launch costs into the ground.”
Varda’s commercial viability remains unproven, and no space-manufactured drugs are currently on pharmacy shelves. But the virtuous cycle Bruey imagines won’t just benefit Varda. Lower launch costs make space accessible for other industries, including semiconductors, fiber optics, and exotic materials – everything that benefits from microgravity but can’t yet justify the expense.
Eventually, Bruey tells his team, launch costs will get so low that it will be cheaper to put an employee in orbit for a month because creating additional automation would cost more.
“I imagine ‘Jane’ goes to space for a month. It’ll be like [heading to] an oil rig. She works at the drug factory for a month, comes back down, and [becomes] the first person ever to go to space and back where she generate[s] more value than the cost to take her there.”
It’s at that moment, Bruey says, when “the invisible hand of the free market economy lifts us off our home planet.”
The near-death experience
The path to those shooting star drug deliveries nearly ended before it began, Bruey told TechCrunch.
Varda launched W-1 in June 2023 aboard a SpaceX Falcon 9 rideshare mission. The pharmaceutical manufacturing process inside the capsule worked as planned, producing crystals of Form III ritonavir, a specific crystalline structure of the drug that’s difficult to create on Earth. The experiments were completed within weeks.
But then the capsule just . . . stayed in orbit. For six months. The problem wasn’t technical, Bruey said; Varda couldn’t get approval to bring its W-1 capsule home.
The Utah Test and Training Range, where Varda wanted to land, exists to “test weapons and train warriors,” as Bruey put it. Space drugs didn’t fall into that category, so Varda wasn’t a priority customer. When higher-priority military missions needed the range, they bumped Varda’s scheduled landing windows. Each bump invalidated the company’s reentry license with the FAA, requiring it to start the approval process over.
“There were 80 people in the office who had spent two and a half years of their lives on this thing, and it’s in orbit, but we’re not sure if it can come home,” Bruey recalled.
The situation looked bad from the outside. To observers, it seemed like Varda had been reckless and launched without proper approvals. But he said in reality, the FAA had authorized Varda to launch without a finalized reentry license because the agency wanted to encourage the nascent commercial reentry industry.
The FAA had authorized Varda to launch without a finalized reentry license, encouraging the nascent commercial reentry industry.
“They encouraged us to proceed with our launch, with the goal being that we would continue to coordinate that license, as well as the use of reentry timing with the range, while we were in orbit,” Bruey explained.
The real problem was that this was the first commercial land reentry ever attempted. There was no established process for the Utah range to coordinate with the FAA. Both entities felt like they were shouldering all the liability.
Varda explored every alternative it could think of. Water landing? The capsule doesn’t float; they’d lose it. Australia? Possible, and they started those conversations. But Bruey says he made a call: no half measures.
“Either you have to push the boundaries of regulation to create this future, or you don’t,” he said. “In order for Varda to be successful, we need to land on land regularly. So we just sucked it up and said, ‘Let’s figure this one out.”
While its first mission remained stranded in orbit, the company continued production on the next capsule. It kept hiring.
In February 2024, eight months after launch, W-1 finally came home. It landed as originally planned at the Utah Test and Training Range, the first commercial spacecraft to land on a military test range and the first to land on U.S. soil under the FAA’s Part 450 licensing framework, introduced by the agency in 2021 to make commercial space operations more flexible.
Now Varda has landing sites in both the U.S. and Australia, and it’s the first company to receive an FAA Part 450 operator license that lets it reenter the U.S. without resubmitting full safety documentation for each flight.
Meanwhile, Varda has a secondary business that emerged from necessity: hypersonic testing.
Very few objects ever travel through the atmosphere at Mach 25. The environment at those speeds is extreme and unique: Temperatures reach thousands of degrees, creating a plasma sheath around a vehicle. The air itself undergoes chemical reactions as molecules are ripped apart and recombine. This environment can’t be replicated on Earth, even in the most advanced wind tunnels.
The Air Force and other defense agencies need to test materials, sensors, navigation systems, and communications equipment in real hypersonic conditions. Traditionally, that would require dedicated test flights that cost upwards of $100 million each and involve significant risk.
Varda offers an alternative. Its W-1 capsules are already reentering at Mach 25. The company can embed sensors, test new thermal protection materials, or validate equipment in the actual flight environment rather than in approximations. The capsule is akin to a wind tunnel, and the reentry is the test.
Varda has already flown experiments for the Air Force Research Laboratory, including an optical emission spectroscopy payload that took in-situ measurements of the shock layer during reentry.
Investors are, big surprise, excited about Varda’s story. The company raised $329 million as of its Series C round this past July, most of it earmarked for building out the company’s pharmaceutical lab in El Segundo. It’s also hiring structural biologists and crystallization scientists to work on more complex molecules, eventually including biologics like monoclonal antibodies, which Bruey says is a $210 billion market.
A whole lot has to go right between then and now for Varda to elbow its way into that business, as well as to make a dent in the business it’s currently targeting. But if Bruey is right, “then” is closer than most people might right now imagine.
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![Scientists Found a Continent-Sized Geological Structure Hiding Beneath Antarctica
The East Antarctic Ice Sheet is almost unfathomably huge. Covering about 75% of the entire frigid continent (nearly everything on its side of the Transantarctic Mountains), the sheet covers about 3.9 million square miles (10.2 million square kilometers) and extends down 1.4 miles (2.2 km), on average, before coming into contact with Earth’s surface. At its deepest, the ice plunges down over 3 miles (4.9 km). For decades, scientists assumed that this literally continent-sized block of ice rested on an expansive and stable chunk of Earth’s crust known as a craton. A team of researchers has now complicated that picture—mapping a vast, interconnected geological structure that fans out from a troubling “tectonic deformation.” Beneath this ice sheet, thinner and more geologically recent slices of crusty lithosphere fan out into hidden valleys called “pull-apart basins.” These basins—30 elongated wedge-shaped valleys in total—constitute an entirely new, continental-scale geological region underneath Antarctica, in fact, one which the researchers have named the East Antarctic Fan-Shaped Basin Province (EAFBP). But it’s how they likely formed that has now caught researchers’ attention.
To put it bluntly, it turns out that about 90% of the planet’s fresh water ice may not be on solid ground. Geologist John Goodge called the team’s findings “provocative” in an independent commentary on the new study, published Thursday in the journal Nature Geoscience.
“East Antarctica is typically considered from seismic tomography and geodetics to be ancient and generally stable,” according to Goodge, who studies continental tectonics with the nonprofit Planetary Science Institute. “[But] something else is going on at depth.” Continental divides Goodge speculates that this seemingly “coherent pull-apart system,” as presented in the new study, might help explain a variety of mysterious heat and water flows beneath this ice sheet’s surface, like that enormous subglacial lake identified in 2016 or some of the hundreds more like it.
The study’s authors, led by geophysicist Egidio Armadillo at the University of Genoa in Italy, agreed: “Because these basins underlie about half of the East Antarctic Ice Sheet, they are likely to heavily influence both ice-flow and landscape evolution,” the researchers wrote in their study, also published Thursday in Nature Geoscience. Armadillo’s team, coordinating across Europe and the U.K., developed their new understanding of Antarctica’s hidden bedrock via an exhaustive set of sensory data. Gravitational and magnetic anomalies were mapped via low-altitude airborne surveys. Ground surface features were mapped with seismic tools, using sound waves that vibrate through the ice and ping back information about subglacial landscapes in 3D. The grey, magenta, and cyan lines represent the apparent new fault lines discovered. Credit: Nature Geoscience All of this data—the fruits of “multi-national efforts to image within and below the ice sheet,” as Goodge put it—had already revealed that regions of the continent were “undergoing more rapid movement and ice-mass loss than previously recognized.” Armadillo’s team merely helped to explain why.
The mechanism Armadillo and his colleagues proposed for the formation of these fan-shaped basins is called “distributed rotational extension.” It involves points called Euler poles around which tectonic plates pivot or rotate rather than smash into each other or pull apart. The result is a bit like decks of cards being spread out on a table, thinning out the stack of Earth’s crust as it moves. An icy situation Goodge took pains to spell out the basins’ implications for melting Antarctic ice due to climate change and the risk of rising global sea levels.
The mere existence of these basins, he wrote, “could introduce widespread, systemic instability to the East Antarctic Ice Sheet” via thinner layers of Earth’s crust and more heat flow from below. On top of that, a series of fault-line “troughs” documented between the basins appear “tailor-made to promote outward flow of ice streams from the interior” into the world’s oceans, he said. That said, the team’s findings are unlikely to end this debate. As Goodge noted, Antarctica is “the last continental frontier of scientific exploration.” It’s still a very mysterious place, one that’s challenging to study given its inhospitable temperatures and extreme geography. Its “cryptic subglacial geology” might stay that way for a while. #Scientists #ContinentSized #Geological #Structure #Hiding #Beneath #AntarcticaAntarctica,Geology,mapping,Plate tectonics Scientists Found a Continent-Sized Geological Structure Hiding Beneath Antarctica
The East Antarctic Ice Sheet is almost unfathomably huge. Covering about 75% of the entire frigid continent (nearly everything on its side of the Transantarctic Mountains), the sheet covers about 3.9 million square miles (10.2 million square kilometers) and extends down 1.4 miles (2.2 km), on average, before coming into contact with Earth’s surface. At its deepest, the ice plunges down over 3 miles (4.9 km). For decades, scientists assumed that this literally continent-sized block of ice rested on an expansive and stable chunk of Earth’s crust known as a craton. A team of researchers has now complicated that picture—mapping a vast, interconnected geological structure that fans out from a troubling “tectonic deformation.” Beneath this ice sheet, thinner and more geologically recent slices of crusty lithosphere fan out into hidden valleys called “pull-apart basins.” These basins—30 elongated wedge-shaped valleys in total—constitute an entirely new, continental-scale geological region underneath Antarctica, in fact, one which the researchers have named the East Antarctic Fan-Shaped Basin Province (EAFBP). But it’s how they likely formed that has now caught researchers’ attention.
To put it bluntly, it turns out that about 90% of the planet’s fresh water ice may not be on solid ground. Geologist John Goodge called the team’s findings “provocative” in an independent commentary on the new study, published Thursday in the journal Nature Geoscience.
“East Antarctica is typically considered from seismic tomography and geodetics to be ancient and generally stable,” according to Goodge, who studies continental tectonics with the nonprofit Planetary Science Institute. “[But] something else is going on at depth.” Continental divides Goodge speculates that this seemingly “coherent pull-apart system,” as presented in the new study, might help explain a variety of mysterious heat and water flows beneath this ice sheet’s surface, like that enormous subglacial lake identified in 2016 or some of the hundreds more like it.
The study’s authors, led by geophysicist Egidio Armadillo at the University of Genoa in Italy, agreed: “Because these basins underlie about half of the East Antarctic Ice Sheet, they are likely to heavily influence both ice-flow and landscape evolution,” the researchers wrote in their study, also published Thursday in Nature Geoscience. Armadillo’s team, coordinating across Europe and the U.K., developed their new understanding of Antarctica’s hidden bedrock via an exhaustive set of sensory data. Gravitational and magnetic anomalies were mapped via low-altitude airborne surveys. Ground surface features were mapped with seismic tools, using sound waves that vibrate through the ice and ping back information about subglacial landscapes in 3D. The grey, magenta, and cyan lines represent the apparent new fault lines discovered. Credit: Nature Geoscience All of this data—the fruits of “multi-national efforts to image within and below the ice sheet,” as Goodge put it—had already revealed that regions of the continent were “undergoing more rapid movement and ice-mass loss than previously recognized.” Armadillo’s team merely helped to explain why.
The mechanism Armadillo and his colleagues proposed for the formation of these fan-shaped basins is called “distributed rotational extension.” It involves points called Euler poles around which tectonic plates pivot or rotate rather than smash into each other or pull apart. The result is a bit like decks of cards being spread out on a table, thinning out the stack of Earth’s crust as it moves. An icy situation Goodge took pains to spell out the basins’ implications for melting Antarctic ice due to climate change and the risk of rising global sea levels.
The mere existence of these basins, he wrote, “could introduce widespread, systemic instability to the East Antarctic Ice Sheet” via thinner layers of Earth’s crust and more heat flow from below. On top of that, a series of fault-line “troughs” documented between the basins appear “tailor-made to promote outward flow of ice streams from the interior” into the world’s oceans, he said. That said, the team’s findings are unlikely to end this debate. As Goodge noted, Antarctica is “the last continental frontier of scientific exploration.” It’s still a very mysterious place, one that’s challenging to study given its inhospitable temperatures and extreme geography. Its “cryptic subglacial geology” might stay that way for a while. #Scientists #ContinentSized #Geological #Structure #Hiding #Beneath #AntarcticaAntarctica,Geology,mapping,Plate tectonics](https://gizmodo.com/app/uploads/2026/06/East-Antarctic-Fan-shaped-Basin-Province.jpeg)
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