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Logitech Pro X2 Superstrike Review: This Gaming Mouse Has No Clicks and It’s Perfect
	
Gaming mice used to be at the forefront of exciting features, with brands working hard to gain a competitive edge. Sadly, that hasn’t happened in the last few years, as we’ve slowly gone down the numbers-game road, which isn’t scenic at all. These days, it’s only about which mouse has a DPI reaching high enough to operate a projector screen, or a weight so light it’s difficult to comprehend if you’re even holding something or not. Logitech, however, with its all-new Pro X2 Superstrike, has seen this trend and just said, “yeah, no.”



So, what’s the Pro X2 Superstrike about? It’s a mouse, of course, that takes the clicks of a conventional one and throws them away. Instead, the Superstrike takes a page from the MacBook playbook by borrowing its haptic motors for the clicking mechanism. It’s something that’s never been done before, yet still makes a ton of sense for serious gamers. But are these latency benefits even worth it? To answer this very question, I used the Pro X2 Superstrike for over two weeks. Spoiler alert: it might be the best gaming mouse I’ve used. Here’s why.



        Logitech Pro X2 Superstrike ReviewHisan KidwaiSummaryThe Logitech Pro X2 Superstrike is something genuinely different. The haptic buttons are one-of-a-kind and work exceptionally well for both gaming and general productivity. In fast-paced games, the reduced actuation distance can actually make a noticeable difference to reaction times. The Logitech G Hub software is easy to use and offers plenty of customization, while the lightweight design makes it comfortable for long sessions.
        
        


Design & No Clicks???







Despite the all-new mechanism, which we’ll talk about soon, Logitech hasn’t changed much about the Superstrike’s design. Instead, it bears a striking resemblance to the SuperLight 2, and that’s not a bad thing. I’m a fan of this new Stormtrooper-inspired color with the white shell and black buttons. The shape is fairly standard without all the ergonomic trickery. The finish is smooth, doesn’t attract any fingerprints, and is super easy to clean, if you like eating Doritos like me when gaming. Weight is kept at 61g, for which the company pulled a lot of strings, like using titanium screws and drilling holes in the PCB. While comfort is subjective, my pain-prone wrists did like the Superstrike during long gaming sessions.



Let’s talk buttons and clicks. The two extra buttons on the left side are the standard kind, meaning they push down when you press them. The real magic happens on the left and right clicks. Logitech has developed a new system called HITS (Haptic Inductive Trigger System). It’s a bit of a mouthful for something that means the mouse combines tiny haptic motors with an electrical sensor to register a click. Remember the Hall Effect on the keyboard? It’s pretty much the same thing, except you can change when the click is registered. 







The benefits of this system are pretty obvious. In most mice, the click is activated after 0.6mm of travel. It’s not a lot, but still more than an eSports player in the heat of a battle would like. With the Superstrike, you can set it to activate after just 0.1mm of travel. That’s incredibly sensitive and means your movements will be registered faster than anyone else’s when coming out of a corner in Valorant or CS2. Logitech claims up to a 30ms reduction in latency.



Speaking of those clicks, I do like them a lot. If you’ve used a MacBook trackpad, then these would be familiar. They are not quite as sharp but still really tactile. You can configure how hard the click should be. The feedback at the highest setting is simply lovely, and I’d actually much rather have these than buttons. What makes things even better is the consistency. Usually, when playing games that require rapid right-clicking, you need to press the button at the optimal area to minimize resistance. But with the Superstrike, you can tap anywhere, and both the feedback and actuation would remain the same.



Gaming on the Logitech Pro X2 Superstrike







Let me get one thing straight: the Pro X2 Superstrike won’t make a bad gamer like me into an eSports player. It can, however, put a good player into eSports territory. I noticed that difference right away, when I first used the mouse, and thought, “Yup, this is it.” Logitech’s Hero sensors play beautifully with the HITS system. Sure, DPI can be set to an oblivion-like 44,000, but for the sake of my tiny 27-inch monitor, I kept it between 900 and 2,000. Tracking was more precise than any other mouse I’ve tested.



Let’s talk numbers. For testing, I picked up a generic ASUS mouse that used the same 2.5 GHz connection. The software of choice was AimLabs, a training ground for players to improve their reaction time by quickly hitting different objects on the screen. I first locked in with the regular mouse (three tries) and got an average reaction time of 243ms (not bad, right?). Then I switched to the Superstrike, with the clicks set to activate as soon as possible. In my best attempt, the reaction time was 218ms, which was noticeably better than my usual results. 







But that’s not all the Superstrike has to offer. That’s because it introduces Rapid Triggers to a mouse for the very first time. For the uninitiated, Rapid Triggers are a keyboard technology that allows the keys to reset and re-actuate instantly after a slight lift of your finger.



I loved how it all comes together in games like CS2, where I went from averaging a few kills to at least landing some headshots. And that pretty much explains the Pro X2 Superstrike. It’s the best tool for gaming, and something you can rely on to help climb the eSports ladder.



For all my fellow Excel and Google Sheets users, while Superstrike isn’t really designed for productivity, I still used it as my daily driver for research. The results? I was doing spreadsheets a tad bit quicker thanks to the haptic clicks, which I configured to perfection. After a long day of work, I also noticed that my index finger didn’t hurt as much with a normal mouse.



Software & Customization





I talked about the customization part above, but to reiterate, the G Hub app handles it all. It’s available on both macOS and Windows and works pretty well. The app is neatly laid out with different sections. At the top is Sensitivity, which, as the name suggests, lets you adjust the DPI. If you’re new, Logitech has a bunch of presets baked in for different types of games. You can adjust the XY axis split, too. Beyond that, there are Assignments that let you assign different functions to the buttons and configure macros. The Scroll Wheel section has BHOP mode, designed to prevent activation from accidental bumps on the scroll wheel.



The real star is the HITS Configuration. Here, you adjust the Actuation point, or the point at which the haptic system registers a click. It can be set from a scale of 0-10, with zero requiring the least effort, and is better for gaming. Then there’s the Rapid Trigger adjustment, and lastly, Click Haptics. While a stronger haptic results in higher battery drain, I didn’t worry much as the Superstrike’s battery life is impressive. It lasted more than a week on a single charge, and I used it as my primary work mouse every day for 8 hours, too.



Verdict







At 9.99 or ₹23,995 on Amazon in India, I agree that the Logitech Pro X2 Superstrike is a premium mouse. But unlike others, it’s something genuinely different. The haptic buttons are one-of-a-kind and work exceptionally well for both gaming and general productivity. In fast-paced games, the reduced actuation distance can actually make a noticeable difference to reaction times. The Logitech G Hub software is easy to use and offers plenty of customization, while the lightweight design makes it comfortable for long sessions. I’m sure we’ll see this tech being copied by others, but until then, if you’re shopping for a serious mouse, the Logitech Pro X2 Superstrike should be on your list.

#Logitech #Pro #Superstrike #Review #Gaming #Mouse #Clicks #Perfectlogitech

Logitech Pro X2 Superstrike Review: This Gaming Mouse Has No Clicks and It’s Perfect

Gaming mice used to be at the forefront of exciting features, with brands working hard to gain a competitive edge. Sadly, that hasn’t happened in the last few years, as we’ve slowly gone down the numbers-game road, which isn’t scenic at all. These days, it’s only about which mouse has a DPI reaching high enough to operate a projector screen, or a weight so light it’s difficult to comprehend if you’re even holding something or not. Logitech, however, with its all-new Pro X2 Superstrike, has seen this trend and just said, “yeah, no.”

So, what’s the Pro X2 Superstrike about? It’s a mouse, of course, that takes the clicks of a conventional one and throws them away. Instead, the Superstrike takes a page from the MacBook playbook by borrowing its haptic motors for the clicking mechanism. It’s something that’s never been done before, yet still makes a ton of sense for serious gamers. But are these latency benefits even worth it? To answer this very question, I used the Pro X2 Superstrike for over two weeks. Spoiler alert: it might be the best gaming mouse I’ve used. Here’s why.

Logitech Pro X2 Superstrike Review

Hisan Kidwai

Summary

The Logitech Pro X2 Superstrike is something genuinely different. The haptic buttons are one-of-a-kind and work exceptionally well for both gaming and general productivity. In fast-paced games, the reduced actuation distance can actually make a noticeable difference to reaction times. The Logitech G Hub software is easy to use and offers plenty of customization, while the lightweight design makes it comfortable for long sessions.

Design & No Clicks???

Logitech Pro X2 Superstrike Review: This Gaming Mouse Has No Clicks and It’s Perfect
	
Gaming mice used to be at the forefront of exciting features, with brands working hard to gain a competitive edge. Sadly, that hasn’t happened in the last few years, as we’ve slowly gone down the numbers-game road, which isn’t scenic at all. These days, it’s only about which mouse has a DPI reaching high enough to operate a projector screen, or a weight so light it’s difficult to comprehend if you’re even holding something or not. Logitech, however, with its all-new Pro X2 Superstrike, has seen this trend and just said, “yeah, no.”



So, what’s the Pro X2 Superstrike about? It’s a mouse, of course, that takes the clicks of a conventional one and throws them away. Instead, the Superstrike takes a page from the MacBook playbook by borrowing its haptic motors for the clicking mechanism. It’s something that’s never been done before, yet still makes a ton of sense for serious gamers. But are these latency benefits even worth it? To answer this very question, I used the Pro X2 Superstrike for over two weeks. Spoiler alert: it might be the best gaming mouse I’ve used. Here’s why.



        Logitech Pro X2 Superstrike ReviewHisan KidwaiSummaryThe Logitech Pro X2 Superstrike is something genuinely different. The haptic buttons are one-of-a-kind and work exceptionally well for both gaming and general productivity. In fast-paced games, the reduced actuation distance can actually make a noticeable difference to reaction times. The Logitech G Hub software is easy to use and offers plenty of customization, while the lightweight design makes it comfortable for long sessions.
        
        


Design & No Clicks???







Despite the all-new mechanism, which we’ll talk about soon, Logitech hasn’t changed much about the Superstrike’s design. Instead, it bears a striking resemblance to the SuperLight 2, and that’s not a bad thing. I’m a fan of this new Stormtrooper-inspired color with the white shell and black buttons. The shape is fairly standard without all the ergonomic trickery. The finish is smooth, doesn’t attract any fingerprints, and is super easy to clean, if you like eating Doritos like me when gaming. Weight is kept at 61g, for which the company pulled a lot of strings, like using titanium screws and drilling holes in the PCB. While comfort is subjective, my pain-prone wrists did like the Superstrike during long gaming sessions.



Let’s talk buttons and clicks. The two extra buttons on the left side are the standard kind, meaning they push down when you press them. The real magic happens on the left and right clicks. Logitech has developed a new system called HITS (Haptic Inductive Trigger System). It’s a bit of a mouthful for something that means the mouse combines tiny haptic motors with an electrical sensor to register a click. Remember the Hall Effect on the keyboard? It’s pretty much the same thing, except you can change when the click is registered. 







The benefits of this system are pretty obvious. In most mice, the click is activated after 0.6mm of travel. It’s not a lot, but still more than an eSports player in the heat of a battle would like. With the Superstrike, you can set it to activate after just 0.1mm of travel. That’s incredibly sensitive and means your movements will be registered faster than anyone else’s when coming out of a corner in Valorant or CS2. Logitech claims up to a 30ms reduction in latency.



Speaking of those clicks, I do like them a lot. If you’ve used a MacBook trackpad, then these would be familiar. They are not quite as sharp but still really tactile. You can configure how hard the click should be. The feedback at the highest setting is simply lovely, and I’d actually much rather have these than buttons. What makes things even better is the consistency. Usually, when playing games that require rapid right-clicking, you need to press the button at the optimal area to minimize resistance. But with the Superstrike, you can tap anywhere, and both the feedback and actuation would remain the same.



Gaming on the Logitech Pro X2 Superstrike







Let me get one thing straight: the Pro X2 Superstrike won’t make a bad gamer like me into an eSports player. It can, however, put a good player into eSports territory. I noticed that difference right away, when I first used the mouse, and thought, “Yup, this is it.” Logitech’s Hero sensors play beautifully with the HITS system. Sure, DPI can be set to an oblivion-like 44,000, but for the sake of my tiny 27-inch monitor, I kept it between 900 and 2,000. Tracking was more precise than any other mouse I’ve tested.



Let’s talk numbers. For testing, I picked up a generic ASUS mouse that used the same 2.5 GHz connection. The software of choice was AimLabs, a training ground for players to improve their reaction time by quickly hitting different objects on the screen. I first locked in with the regular mouse (three tries) and got an average reaction time of 243ms (not bad, right?). Then I switched to the Superstrike, with the clicks set to activate as soon as possible. In my best attempt, the reaction time was 218ms, which was noticeably better than my usual results. 







But that’s not all the Superstrike has to offer. That’s because it introduces Rapid Triggers to a mouse for the very first time. For the uninitiated, Rapid Triggers are a keyboard technology that allows the keys to reset and re-actuate instantly after a slight lift of your finger.



I loved how it all comes together in games like CS2, where I went from averaging a few kills to at least landing some headshots. And that pretty much explains the Pro X2 Superstrike. It’s the best tool for gaming, and something you can rely on to help climb the eSports ladder.



For all my fellow Excel and Google Sheets users, while Superstrike isn’t really designed for productivity, I still used it as my daily driver for research. The results? I was doing spreadsheets a tad bit quicker thanks to the haptic clicks, which I configured to perfection. After a long day of work, I also noticed that my index finger didn’t hurt as much with a normal mouse.



Software & Customization





I talked about the customization part above, but to reiterate, the G Hub app handles it all. It’s available on both macOS and Windows and works pretty well. The app is neatly laid out with different sections. At the top is Sensitivity, which, as the name suggests, lets you adjust the DPI. If you’re new, Logitech has a bunch of presets baked in for different types of games. You can adjust the XY axis split, too. Beyond that, there are Assignments that let you assign different functions to the buttons and configure macros. The Scroll Wheel section has BHOP mode, designed to prevent activation from accidental bumps on the scroll wheel.



The real star is the HITS Configuration. Here, you adjust the Actuation point, or the point at which the haptic system registers a click. It can be set from a scale of 0-10, with zero requiring the least effort, and is better for gaming. Then there’s the Rapid Trigger adjustment, and lastly, Click Haptics. While a stronger haptic results in higher battery drain, I didn’t worry much as the Superstrike’s battery life is impressive. It lasted more than a week on a single charge, and I used it as my primary work mouse every day for 8 hours, too.



Verdict







At 9.99 or ₹23,995 on Amazon in India, I agree that the Logitech Pro X2 Superstrike is a premium mouse. But unlike others, it’s something genuinely different. The haptic buttons are one-of-a-kind and work exceptionally well for both gaming and general productivity. In fast-paced games, the reduced actuation distance can actually make a noticeable difference to reaction times. The Logitech G Hub software is easy to use and offers plenty of customization, while the lightweight design makes it comfortable for long sessions. I’m sure we’ll see this tech being copied by others, but until then, if you’re shopping for a serious mouse, the Logitech Pro X2 Superstrike should be on your list.

#Logitech #Pro #Superstrike #Review #Gaming #Mouse #Clicks #Perfectlogitech

Despite the all-new mechanism, which we’ll talk about soon, Logitech hasn’t changed much about the Superstrike’s design. Instead, it bears a striking resemblance to the SuperLight 2, and that’s not a bad thing. I’m a fan of this new Stormtrooper-inspired color with the white shell and black buttons. The shape is fairly standard without all the ergonomic trickery. The finish is smooth, doesn’t attract any fingerprints, and is super easy to clean, if you like eating Doritos like me when gaming. Weight is kept at 61g, for which the company pulled a lot of strings, like using titanium screws and drilling holes in the PCB. While comfort is subjective, my pain-prone wrists did like the Superstrike during long gaming sessions.

Let’s talk buttons and clicks. The two extra buttons on the left side are the standard kind, meaning they push down when you press them. The real magic happens on the left and right clicks. Logitech has developed a new system called HITS (Haptic Inductive Trigger System). It’s a bit of a mouthful for something that means the mouse combines tiny haptic motors with an electrical sensor to register a click. Remember the Hall Effect on the keyboard? It’s pretty much the same thing, except you can change when the click is registered.

Closeup of the HITS clicks

The benefits of this system are pretty obvious. In most mice, the click is activated after 0.6mm of travel. It’s not a lot, but still more than an eSports player in the heat of a battle would like. With the Superstrike, you can set it to activate after just 0.1mm of travel. That’s incredibly sensitive and means your movements will be registered faster than anyone else’s when coming out of a corner in Valorant or CS2. Logitech claims up to a 30ms reduction in latency.

Speaking of those clicks, I do like them a lot. If you’ve used a MacBook trackpad, then these would be familiar. They are not quite as sharp but still really tactile. You can configure how hard the click should be. The feedback at the highest setting is simply lovely, and I’d actually much rather have these than buttons. What makes things even better is the consistency. Usually, when playing games that require rapid right-clicking, you need to press the button at the optimal area to minimize resistance. But with the Superstrike, you can tap anywhere, and both the feedback and actuation would remain the same.

Gaming on the Logitech Pro X2 Superstrike

A person gaming on the Logitech Pro X2 Superstrike

Let me get one thing straight: the Pro X2 Superstrike won’t make a bad gamer like me into an eSports player. It can, however, put a good player into eSports territory. I noticed that difference right away, when I first used the mouse, and thought, “Yup, this is it.” Logitech’s Hero sensors play beautifully with the HITS system. Sure, DPI can be set to an oblivion-like 44,000, but for the sake of my tiny 27-inch monitor, I kept it between 900 and 2,000. Tracking was more precise than any other mouse I’ve tested.

Let’s talk numbers. For testing, I picked up a generic ASUS mouse that used the same 2.5 GHz connection. The software of choice was AimLabs, a training ground for players to improve their reaction time by quickly hitting different objects on the screen. I first locked in with the regular mouse (three tries) and got an average reaction time of 243ms (not bad, right?). Then I switched to the Superstrike, with the clicks set to activate as soon as possible. In my best attempt, the reaction time was 218ms, which was noticeably better than my usual results.

Logitech Pro X2 Superstrike against a regular Asus mouse

But that’s not all the Superstrike has to offer. That’s because it introduces Rapid Triggers to a mouse for the very first time. For the uninitiated, Rapid Triggers are a keyboard technology that allows the keys to reset and re-actuate instantly after a slight lift of your finger.

I loved how it all comes together in games like CS2, where I went from averaging a few kills to at least landing some headshots. And that pretty much explains the Pro X2 Superstrike. It’s the best tool for gaming, and something you can rely on to help climb the eSports ladder.

For all my fellow Excel and Google Sheets users, while Superstrike isn’t really designed for productivity, I still used it as my daily driver for research. The results? I was doing spreadsheets a tad bit quicker thanks to the haptic clicks, which I configured to perfection. After a long day of work, I also noticed that my index finger didn’t hurt as much with a normal mouse.

Software & Customization

I talked about the customization part above, but to reiterate, the G Hub app handles it all. It’s available on both macOS and Windows and works pretty well. The app is neatly laid out with different sections. At the top is Sensitivity, which, as the name suggests, lets you adjust the DPI. If you’re new, Logitech has a bunch of presets baked in for different types of games. You can adjust the XY axis split, too. Beyond that, there are Assignments that let you assign different functions to the buttons and configure macros. The Scroll Wheel section has BHOP mode, designed to prevent activation from accidental bumps on the scroll wheel.

The real star is the HITS Configuration. Here, you adjust the Actuation point, or the point at which the haptic system registers a click. It can be set from a scale of 0-10, with zero requiring the least effort, and is better for gaming. Then there’s the Rapid Trigger adjustment, and lastly, Click Haptics. While a stronger haptic results in higher battery drain, I didn’t worry much as the Superstrike’s battery life is impressive. It lasted more than a week on a single charge, and I used it as my primary work mouse every day for 8 hours, too.

Verdict

Logitech Pro X2 Superstrike from the back

At $189.99 or ₹23,995 on Amazon in India, I agree that the Logitech Pro X2 Superstrike is a premium mouse. But unlike others, it’s something genuinely different. The haptic buttons are one-of-a-kind and work exceptionally well for both gaming and general productivity. In fast-paced games, the reduced actuation distance can actually make a noticeable difference to reaction times. The Logitech G Hub software is easy to use and offers plenty of customization, while the lightweight design makes it comfortable for long sessions. I’m sure we’ll see this tech being copied by others, but until then, if you’re shopping for a serious mouse, the Logitech Pro X2 Superstrike should be on your list.

#Logitech #Pro #Superstrike #Review #Gaming #Mouse #Clicks #Perfectlogitech

Gaming mice used to be at the forefront of exciting features, with brands working hard to gain a competitive edge. Sadly, that hasn’t happened in the last few years, as we’ve slowly gone down the numbers-game road, which isn’t scenic at all. These days, it’s only about which mouse has a DPI reaching high enough to operate a projector screen, or a weight so light it’s difficult to comprehend if you’re even holding something or not. Logitech, however, with its all-new Pro X2 Superstrike, has seen this trend and just said, “yeah, no.”

So, what’s the Pro X2 Superstrike about? It’s a mouse, of course, that takes the clicks of a conventional one and throws them away. Instead, the Superstrike takes a page from the MacBook playbook by borrowing its haptic motors for the clicking mechanism. It’s something that’s never been done before, yet still makes a ton of sense for serious gamers. But are these latency benefits even worth it? To answer this very question, I used the Pro X2 Superstrike for over two weeks. Spoiler alert: it might be the best gaming mouse I’ve used. Here’s why.

Logitech Pro X2 Superstrike Review

Hisan Kidwai

Summary

The Logitech Pro X2 Superstrike is something genuinely different. The haptic buttons are one-of-a-kind and work exceptionally well for both gaming and general productivity. In fast-paced games, the reduced actuation distance can actually make a noticeable difference to reaction times. The Logitech G Hub software is easy to use and offers plenty of customization, while the lightweight design makes it comfortable for long sessions.

Design & No Clicks???

Despite the all-new mechanism, which we’ll talk about soon, Logitech hasn’t changed much about the Superstrike’s design. Instead, it bears a striking resemblance to the SuperLight 2, and that’s not a bad thing. I’m a fan of this new Stormtrooper-inspired color with the white shell and black buttons. The shape is fairly standard without all the ergonomic trickery. The finish is smooth, doesn’t attract any fingerprints, and is super easy to clean, if you like eating Doritos like me when gaming. Weight is kept at 61g, for which the company pulled a lot of strings, like using titanium screws and drilling holes in the PCB. While comfort is subjective, my pain-prone wrists did like the Superstrike during long gaming sessions.

Let’s talk buttons and clicks. The two extra buttons on the left side are the standard kind, meaning they push down when you press them. The real magic happens on the left and right clicks. Logitech has developed a new system called HITS (Haptic Inductive Trigger System). It’s a bit of a mouthful for something that means the mouse combines tiny haptic motors with an electrical sensor to register a click. Remember the Hall Effect on the keyboard? It’s pretty much the same thing, except you can change when the click is registered.

Closeup of the HITS clicks

The benefits of this system are pretty obvious. In most mice, the click is activated after 0.6mm of travel. It’s not a lot, but still more than an eSports player in the heat of a battle would like. With the Superstrike, you can set it to activate after just 0.1mm of travel. That’s incredibly sensitive and means your movements will be registered faster than anyone else’s when coming out of a corner in Valorant or CS2. Logitech claims up to a 30ms reduction in latency.

Speaking of those clicks, I do like them a lot. If you’ve used a MacBook trackpad, then these would be familiar. They are not quite as sharp but still really tactile. You can configure how hard the click should be. The feedback at the highest setting is simply lovely, and I’d actually much rather have these than buttons. What makes things even better is the consistency. Usually, when playing games that require rapid right-clicking, you need to press the button at the optimal area to minimize resistance. But with the Superstrike, you can tap anywhere, and both the feedback and actuation would remain the same.

Gaming on the Logitech Pro X2 Superstrike

A person gaming on the Logitech Pro X2 Superstrike

Let me get one thing straight: the Pro X2 Superstrike won’t make a bad gamer like me into an eSports player. It can, however, put a good player into eSports territory. I noticed that difference right away, when I first used the mouse, and thought, “Yup, this is it.” Logitech’s Hero sensors play beautifully with the HITS system. Sure, DPI can be set to an oblivion-like 44,000, but for the sake of my tiny 27-inch monitor, I kept it between 900 and 2,000. Tracking was more precise than any other mouse I’ve tested.

Let’s talk numbers. For testing, I picked up a generic ASUS mouse that used the same 2.5 GHz connection. The software of choice was AimLabs, a training ground for players to improve their reaction time by quickly hitting different objects on the screen. I first locked in with the regular mouse (three tries) and got an average reaction time of 243ms (not bad, right?). Then I switched to the Superstrike, with the clicks set to activate as soon as possible. In my best attempt, the reaction time was 218ms, which was noticeably better than my usual results.

Logitech Pro X2 Superstrike against a regular Asus mouse

But that’s not all the Superstrike has to offer. That’s because it introduces Rapid Triggers to a mouse for the very first time. For the uninitiated, Rapid Triggers are a keyboard technology that allows the keys to reset and re-actuate instantly after a slight lift of your finger.

I loved how it all comes together in games like CS2, where I went from averaging a few kills to at least landing some headshots. And that pretty much explains the Pro X2 Superstrike. It’s the best tool for gaming, and something you can rely on to help climb the eSports ladder.

For all my fellow Excel and Google Sheets users, while Superstrike isn’t really designed for productivity, I still used it as my daily driver for research. The results? I was doing spreadsheets a tad bit quicker thanks to the haptic clicks, which I configured to perfection. After a long day of work, I also noticed that my index finger didn’t hurt as much with a normal mouse.

Software & Customization

I talked about the customization part above, but to reiterate, the G Hub app handles it all. It’s available on both macOS and Windows and works pretty well. The app is neatly laid out with different sections. At the top is Sensitivity, which, as the name suggests, lets you adjust the DPI. If you’re new, Logitech has a bunch of presets baked in for different types of games. You can adjust the XY axis split, too. Beyond that, there are Assignments that let you assign different functions to the buttons and configure macros. The Scroll Wheel section has BHOP mode, designed to prevent activation from accidental bumps on the scroll wheel.

The real star is the HITS Configuration. Here, you adjust the Actuation point, or the point at which the haptic system registers a click. It can be set from a scale of 0-10, with zero requiring the least effort, and is better for gaming. Then there’s the Rapid Trigger adjustment, and lastly, Click Haptics. While a stronger haptic results in higher battery drain, I didn’t worry much as the Superstrike’s battery life is impressive. It lasted more than a week on a single charge, and I used it as my primary work mouse every day for 8 hours, too.

Verdict

Logitech Pro X2 Superstrike from the back

At $189.99 or ₹23,995 on Amazon in India, I agree that the Logitech Pro X2 Superstrike is a premium mouse. But unlike others, it’s something genuinely different. The haptic buttons are one-of-a-kind and work exceptionally well for both gaming and general productivity. In fast-paced games, the reduced actuation distance can actually make a noticeable difference to reaction times. The Logitech G Hub software is easy to use and offers plenty of customization, while the lightweight design makes it comfortable for long sessions. I’m sure we’ll see this tech being copied by others, but until then, if you’re shopping for a serious mouse, the Logitech Pro X2 Superstrike should be on your list.

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Romero out for season, but De Zerbi backs Tottenham Hotspur for Premier League survival <div id="content-body-70874795" itemprop="articleBody"><p>Roberto De Zerbi confirmed on Friday that Cristian Romero will miss the rest of Tottenham’s battle for Premier League survival, but remains optimistic that just one win can transform his side’s fortunes.</p><p>Romero suffered a knee injury, which could also endanger his place in Argentina’s World Cup squad, during last weekend’s 1-0 defeat by Sunderland in De Zerbi’s first match in charge.</p><p>“I am really sorry for him and his injury,” said De Zerbi.</p><p>“Romero first of all loves Tottenham and the people have to know he is suffering for this injury and because he cannot play any more for us this season,” he added.</p><p>Without a win in 14 league games, Spurs are two points adrift of safety with six matches of the campaign to go.</p><p>But victory against De Zerbi’s former club Brighton on Saturday would propel Tottenham out of the bottom three for at least 48 hours.</p><p>“I think it is crucial to win a game not just for the table. Of course, one part of the table for sure, but we have to feel again what it is nice to win a game and what it can do. I have no doubts about the quality of the players,” De Zerbi said.</p><p><b>ALSO READ | <a href="https://sportstar.thehindu.com/football/epl/saka-injury-news-arsenal-vs-manchester-city-premier-league-title-race-decider/article70874269.ece" target="_blank" rel="nofollow">Arteta rules out Saka for Arsenal vs Manchester City clash</a></b></p><p>In a bid to build team chemistry, De Zerbi took his players out to dinner this week in London’s Mayfair. The Italian is happy to pick up the bill for more dinners in the coming weeks if he is rewarded with results on the field.</p><p>“The food was amazing and if we win, I am ready to pay every week for one dinner,” said the former Marseille coach.</p><p>“I am positive, I am ready to fight, and I believe in keeping Premier League (status). I believe in the words that I said last week. The focus is to win one game,” he added.</p><p>Rodrigo Bentancur could make his return from a three-month injury layoff against the Seagulls. However, first-choice goalkeeper Guglielmo Vicario remains out after surgery on a hernia.</p><p class="publish-time" id="end-of-article">Published on Apr 17, 2026</p></div> #Romero #season #Zerbi #backs #Tottenham #Hotspur #Premier #League #survival

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Deadspin | Toronto FC eager to continue to collect points vs. Austin FC <div id=""><section id="0" class=" w-full"><div class="xl:container mx-0 !px-4 py-0 pb-4 !mx-0 !px-0"><img src="https://images.deadspin.com/tr:w-900/28708035.jpg" srcset="https://images.deadspin.com/tr:w-900/28708035.jpg" alt="MLS: FC Cincinnati at Toronto FC" class="w-full" fetchpriority="high" loading="eager"/><span class="text-0.8 leading-tight">Apr 11, 2026; Toronto, Ontario, CAN; Toronto FC midfielder Malik Henry (78) reacts after an own goal by FC Cincinnati during the second half at BMO Field. Mandatory Credit: John E. Sokolowski-Imagn Images<!-- --> <!-- --> </span></div></section><section id="section-1"> <p>Toronto FC will look to build on a seven-week undefeated stretch when they host offensively challenged Austin FC Saturday afternoon.</p> </section><section id="section-2"> <p>The Reds (3-2-2, 11 points) reside in sixth place in the Eastern Conference despite conceding more goals (11) and they have scored (10). </p> </section><section id="section-3"> <p>Toronto earned points in its past five matches, winning three of those before recording a 1-1 draw at home with FC Cincinnati on April 11. In that match, the Reds were the beneficiary of a red card that gave them a man advantage for the final 19-plus minutes and an own goal by the visitors in the 83rd minute.</p> </section><section id="section-4"> <p>Toronto carried that margin into added time when it conceded a goal.</p> </section><section id="section-5"> <p>“We’ve given up three goals being up a man in the last two weeks, and that should never happen,” Reds coach Robin Fraser said. “It’s always a positive at least that you’re picking up points.”</p> </section><br/><section id="section-6"> <p>Toronto has not lost since falling at Vancouver 3-0 on Feb. 28 and is unbeaten in its past 11 home matches (4-0-7) since June 25, 2025.</p> </section> <section id="section-7"> <p>“We’re gaining points, and it’s better than last year (when) we weren’t doing that,” Toronto goalkeeper Luka Gavran said.</p> </section><section id="section-8"> <p>Austin FC (1-3-3, 6 points), meanwhile, will look to escape a swoon that’s seen them go winless since March 1. The team’s most recent league setback was a 2-1 loss at home to the Los Angeles Galaxy on April 11. Austin’s skid was exacerbated by a 2-1 loss at Louisville City on Wednesday in the U.S. Open Cup’s Round of 32.</p> </section><section id="section-9"> <p>Austin FC trailed 2-0 in both of those contests and only managed to halve their deficits in each — with the goals in both of the losses coming in the second half on set pieces. Austin has scored five of its nine goals this season (which includes an own goal) from corner kicks or free kicks.</p> </section><section id="section-10"> <p>“Even though we didn’t have a good first half, we could score two or three goals [before halftime],” Austin coach Nico Estevez said after the most recent setback. “I think in the second half, we could score like three, four goals also, and it’s unlucky that we didn’t.”</p> </section><section id="section-11"> <p>Playmaking midfielder Owen Wolff could return on Saturday for Austin after missing the first seven MLS matches and the U.S. Open contest following sports hernia surgery.</p> </section><br/><section id="section-12"> <p>–Field Level Media</p> </section> </div> #Deadspin #Toronto #eager #continue #collect #points #Austin

officially unveiled the Luna Band, a new voice-first wearable designed to help users improve their daily routines through real-time health tracking. Supported by the company’s LifeOS intelligence system, the wearable continuously monitors body signals and transforms them into personalized recommendations. Luna designed the device for people who want smarter support for productivity, recovery, and overall health. The invite-only Drop 1 is expected to begin shipping by the end of July 2026.

Luna Band: Key Highlights

Luna designed the Luna app to make health tracking simpler and more organized by consolidating several wellness features into a single platform. This app integrates features that involve stress management, nutrition, exercise, supplements, and recovery into a single application. Another customization option available to users is creating personal health modules in the app.

The application brings together aspects of stress, diet, fitness, nutritional supplements, and productivity within the app’s micro-apps. Users can also sync third-party devices and other relevant health-related data sources for a more personalized experience.

Luna Introduces Luna Band With Real-Time Health Tracking Features
	
Luna has officially unveiled the Luna Band, a new voice-first wearable designed to help users improve their daily routines through real-time health tracking. Supported by the company’s LifeOS intelligence system, the wearable continuously monitors body signals and transforms them into personalized recommendations. Luna designed the device for people who want smarter support for productivity, recovery, and overall health. The invite-only Drop 1 is expected to begin shipping by the end of July 2026.



Luna Band: Key Highlights



Luna designed the Luna app to make health tracking simpler and more organized by consolidating several wellness features into a single platform. This app integrates features that involve stress management, nutrition, exercise, supplements, and recovery into a single application. Another customization option available to users is creating personal health modules in the app.



The application brings together aspects of stress, diet, fitness, nutritional supplements, and productivity within the app’s micro-apps. Users can also sync third-party devices and other relevant health-related data sources for a more personalized experience.







The company also allows users to create their own health modules in the app rather than relying solely on prebuilt features. Alongside this, Luna highlights its voice-logging feature, which eliminates the need for manual data entry. Users can quickly record meals, workouts, and daily habits through simple voice commands, making health tracking faster.



Luna designed LifeOS as one of its main AI-powered features to simplify health tracking through personalized insights and recommendations. The system continuously studies body signals, lifestyle habits, biomarkers, and health trends to deliver a better understanding of overall wellness. Luna says LifeOS is included with the Luna Band platform.



Price and Availability



Luna has confirmed that the first release of the Luna Band, called Drop 1, will be available through an invite-only system. Users interested in the wearable can sign up through the company’s official waitlist before shipping starts later in July 2026. 

#Luna #Introduces #Luna #Band #RealTime #Health #Tracking #FeaturesLuna

The company also allows users to create their own health modules in the app rather than relying solely on prebuilt features. Alongside this, Luna highlights its voice-logging feature, which eliminates the need for manual data entry. Users can quickly record meals, workouts, and daily habits through simple voice commands, making health tracking faster.

Luna designed LifeOS as one of its main AI-powered features to simplify health tracking through personalized insights and recommendations. The system continuously studies body signals, lifestyle habits, biomarkers, and health trends to deliver a better understanding of overall wellness. Luna says LifeOS is included with the Luna Band platform.

Price and Availability

Luna has confirmed that the first release of the Luna Band, called Drop 1, will be available through an invite-only system. Users interested in the wearable can sign up through the company’s official waitlist before shipping starts later in July 2026.

#Luna #Introduces #Luna #Band #RealTime #Health #Tracking #FeaturesLuna">Luna Introduces Luna Band With Real-Time Health Tracking Features
	
Luna has officially unveiled the Luna Band, a new voice-first wearable designed to help users improve their daily routines through real-time health tracking. Supported by the company’s LifeOS intelligence system, the wearable continuously monitors body signals and transforms them into personalized recommendations. Luna designed the device for people who want smarter support for productivity, recovery, and overall health. The invite-only Drop 1 is expected to begin shipping by the end of July 2026.



Luna Band: Key Highlights



Luna designed the Luna app to make health tracking simpler and more organized by consolidating several wellness features into a single platform. This app integrates features that involve stress management, nutrition, exercise, supplements, and recovery into a single application. Another customization option available to users is creating personal health modules in the app.



The application brings together aspects of stress, diet, fitness, nutritional supplements, and productivity within the app’s micro-apps. Users can also sync third-party devices and other relevant health-related data sources for a more personalized experience.







The company also allows users to create their own health modules in the app rather than relying solely on prebuilt features. Alongside this, Luna highlights its voice-logging feature, which eliminates the need for manual data entry. Users can quickly record meals, workouts, and daily habits through simple voice commands, making health tracking faster.



Luna designed LifeOS as one of its main AI-powered features to simplify health tracking through personalized insights and recommendations. The system continuously studies body signals, lifestyle habits, biomarkers, and health trends to deliver a better understanding of overall wellness. Luna says LifeOS is included with the Luna Band platform.



Price and Availability



Luna has confirmed that the first release of the Luna Band, called Drop 1, will be available through an invite-only system. Users interested in the wearable can sign up through the company’s official waitlist before shipping starts later in July 2026. 

#Luna #Introduces #Luna #Band #RealTime #Health #Tracking #FeaturesLuna

the Luna Band, a new voice-first wearable designed to help users improve their daily routines through real-time health tracking. Supported by the company’s LifeOS intelligence system, the wearable continuously monitors body signals and transforms them into personalized recommendations. Luna designed the device for people who want smarter support for productivity, recovery, and overall health. The invite-only Drop 1 is expected to begin shipping by the end of July 2026.

Luna Band: Key Highlights

Luna designed the Luna app to make health tracking simpler and more organized by consolidating several wellness features into a single platform. This app integrates features that involve stress management, nutrition, exercise, supplements, and recovery into a single application. Another customization option available to users is creating personal health modules in the app.

The application brings together aspects of stress, diet, fitness, nutritional supplements, and productivity within the app’s micro-apps. Users can also sync third-party devices and other relevant health-related data sources for a more personalized experience.

Luna Introduces Luna Band With Real-Time Health Tracking Features
	
Luna has officially unveiled the Luna Band, a new voice-first wearable designed to help users improve their daily routines through real-time health tracking. Supported by the company’s LifeOS intelligence system, the wearable continuously monitors body signals and transforms them into personalized recommendations. Luna designed the device for people who want smarter support for productivity, recovery, and overall health. The invite-only Drop 1 is expected to begin shipping by the end of July 2026.



Luna Band: Key Highlights



Luna designed the Luna app to make health tracking simpler and more organized by consolidating several wellness features into a single platform. This app integrates features that involve stress management, nutrition, exercise, supplements, and recovery into a single application. Another customization option available to users is creating personal health modules in the app.



The application brings together aspects of stress, diet, fitness, nutritional supplements, and productivity within the app’s micro-apps. Users can also sync third-party devices and other relevant health-related data sources for a more personalized experience.







The company also allows users to create their own health modules in the app rather than relying solely on prebuilt features. Alongside this, Luna highlights its voice-logging feature, which eliminates the need for manual data entry. Users can quickly record meals, workouts, and daily habits through simple voice commands, making health tracking faster.



Luna designed LifeOS as one of its main AI-powered features to simplify health tracking through personalized insights and recommendations. The system continuously studies body signals, lifestyle habits, biomarkers, and health trends to deliver a better understanding of overall wellness. Luna says LifeOS is included with the Luna Band platform.



Price and Availability



Luna has confirmed that the first release of the Luna Band, called Drop 1, will be available through an invite-only system. Users interested in the wearable can sign up through the company’s official waitlist before shipping starts later in July 2026. 

#Luna #Introduces #Luna #Band #RealTime #Health #Tracking #FeaturesLuna

The company also allows users to create their own health modules in the app rather than relying solely on prebuilt features. Alongside this, Luna highlights its voice-logging feature, which eliminates the need for manual data entry. Users can quickly record meals, workouts, and daily habits through simple voice commands, making health tracking faster.

Luna designed LifeOS as one of its main AI-powered features to simplify health tracking through personalized insights and recommendations. The system continuously studies body signals, lifestyle habits, biomarkers, and health trends to deliver a better understanding of overall wellness. Luna says LifeOS is included with the Luna Band platform.

Price and Availability

Luna has confirmed that the first release of the Luna Band, called Drop 1, will be available through an invite-only system. Users interested in the wearable can sign up through the company’s official waitlist before shipping starts later in July 2026.

#Luna #Introduces #Luna #Band #RealTime #Health #Tracking #FeaturesLuna">Luna Introduces Luna Band With Real-Time Health Tracking Features

Luna has officially unveiled the Luna Band, a new voice-first wearable designed to help users improve their daily routines through real-time health tracking. Supported by the company’s LifeOS intelligence system, the wearable continuously monitors body signals and transforms them into personalized recommendations. Luna designed the device for people who want smarter support for productivity, recovery, and overall health. The invite-only Drop 1 is expected to begin shipping by the end of July 2026.

Luna Band: Key Highlights

Luna designed the Luna app to make health tracking simpler and more organized by consolidating several wellness features into a single platform. This app integrates features that involve stress management, nutrition, exercise, supplements, and recovery into a single application. Another customization option available to users is creating personal health modules in the app.

The application brings together aspects of stress, diet, fitness, nutritional supplements, and productivity within the app’s micro-apps. Users can also sync third-party devices and other relevant health-related data sources for a more personalized experience.

Luna Introduces Luna Band With Real-Time Health Tracking Features
	
Luna has officially unveiled the Luna Band, a new voice-first wearable designed to help users improve their daily routines through real-time health tracking. Supported by the company’s LifeOS intelligence system, the wearable continuously monitors body signals and transforms them into personalized recommendations. Luna designed the device for people who want smarter support for productivity, recovery, and overall health. The invite-only Drop 1 is expected to begin shipping by the end of July 2026.



Luna Band: Key Highlights



Luna designed the Luna app to make health tracking simpler and more organized by consolidating several wellness features into a single platform. This app integrates features that involve stress management, nutrition, exercise, supplements, and recovery into a single application. Another customization option available to users is creating personal health modules in the app.



The application brings together aspects of stress, diet, fitness, nutritional supplements, and productivity within the app’s micro-apps. Users can also sync third-party devices and other relevant health-related data sources for a more personalized experience.







The company also allows users to create their own health modules in the app rather than relying solely on prebuilt features. Alongside this, Luna highlights its voice-logging feature, which eliminates the need for manual data entry. Users can quickly record meals, workouts, and daily habits through simple voice commands, making health tracking faster.



Luna designed LifeOS as one of its main AI-powered features to simplify health tracking through personalized insights and recommendations. The system continuously studies body signals, lifestyle habits, biomarkers, and health trends to deliver a better understanding of overall wellness. Luna says LifeOS is included with the Luna Band platform.



Price and Availability



Luna has confirmed that the first release of the Luna Band, called Drop 1, will be available through an invite-only system. Users interested in the wearable can sign up through the company’s official waitlist before shipping starts later in July 2026. 

#Luna #Introduces #Luna #Band #RealTime #Health #Tracking #FeaturesLuna

The company also allows users to create their own health modules in the app rather than relying solely on prebuilt features. Alongside this, Luna highlights its voice-logging feature, which eliminates the need for manual data entry. Users can quickly record meals, workouts, and daily habits through simple voice commands, making health tracking faster.

Luna designed LifeOS as one of its main AI-powered features to simplify health tracking through personalized insights and recommendations. The system continuously studies body signals, lifestyle habits, biomarkers, and health trends to deliver a better understanding of overall wellness. Luna says LifeOS is included with the Luna Band platform.

Price and Availability

Luna has confirmed that the first release of the Luna Band, called Drop 1, will be available through an invite-only system. Users interested in the wearable can sign up through the company’s official waitlist before shipping starts later in July 2026.

#Luna #Introduces #Luna #Band #RealTime #Health #Tracking #FeaturesLuna
suggested that GLP-1s can tamp down people’s unhealthy urges for alcohol, cocaine, and even vices like gambling. And earlier this month, researchers in Denmark published data from the first double-blinded, randomized, and placebo-controlled trial of semaglutide for alcohol use disorder in The Lancet. Over a 26-week period, the study found that people on semaglutide consumed less alcohol than those given a placebo and experienced noticeably fewer heavy drinking days when they did drink.

Can Ozempic Treat Alcoholism? Here’s What You Should Know
                Semaglutide (the active ingredient in Ozempic and Wegovy) and other GLP-1 medications have rapidly become some of the most popular drugs in the world. Originally developed for type 2 diabetes, GLP-1s are now better known for treating obesity. In the near future, though, these drugs could have yet another vital use as treatments for alcohol addiction and other substance use disorders. Over the past few years, a growing base of evidence has suggested that GLP-1s can tamp down people’s unhealthy urges for alcohol, cocaine, and even vices like gambling. And earlier this month, researchers in Denmark published data from the first double-blinded, randomized, and placebo-controlled trial of semaglutide for alcohol use disorder in The Lancet. Over a 26-week period, the study found that people on semaglutide consumed less alcohol than those given a placebo and experienced noticeably fewer heavy drinking days when they did drink. © siamionau pavel via Shutterstock There are other similar studies underway, including in the United States. Some are testing semaglutide for other kinds of substance use disorder, like opioids. Others are testing newer drugs like tirzepatide (a dual agonist that pairs GLP-1 with the hunger-related hormone GIP).

 I reached out to an outside expert, Asim Shah, a professor and executive vice chair of psychiatry and behavioral sciences at Baylor College of Medicine, to talk about the emerging science surrounding GLP-1s and addiction treatment. We discussed the leading theory behind why GLP-1s can reduce addiction, his opinion of the recent Lancet trial, and what it will take for these drugs to be widely adopted as treatments for substance use disorders. The following has been lightly edited for clarity and grammar.

 Ed Cara, Gizmodo: Do we have any sort of sense yet as to how or why GLP-1s seem to be working well against substance use disorders? Asim Shah: So the craving, or pleasure, center of the brain is related to dopamine, which is a brain neurotransmitter. Whenever you crave something and you eat it or you take it, that gives you pleasure. That is the dopamine functioning in the brain. And all of this is related to the same thing, whether it’s a craving for food, craving for smoking, craving for alcohol, any drug. That’s the neurobiological mechanism of craving and pleasure, and it’s all the same mechanism.

 © Mohammed_Al_Ali via Shutterstock And incidentally, we found out that the people who were losing weight on these GLP-1s, they often also stopped smoking cigarettes and their addiction got better with alcohol. It was an incidental finding, but it’s something people are now trying to study more closely. Gizmodo: Speaking of studies, what do you make of the newest trial published in The Lancet this month? Shah: So this was a 26 week study, which had about 100 patients, half and half men and women both. In our world, 100 patients is a medium sized study; a larger one might usually have 300, 400, 600 patients. So this is a medium sized study, which is decent. It’s not bad. And in my opinion, it was done pretty well, not a lot of bias in the study that I saw.

 Now, of course, this is not a definitive study. And you need to follow up with these patients after the weeks of study. We call these start-up studies, and they are what we base future, longer and bigger studies on. So it’s a good base, and there are other studies on the way. Gizmodo: Broadly speaking, what are the questions that these longer and larger studies need to try answering? Shah: So there are a couple of things. These are different substances that people are looking at; one is alcohol, one smoking, the other is opiates. So the next studies we should be doing is to see whether GLP-1s like semaglutide can limit more than one of these addictions. Because the mechanism is the same mechanism for all the cravings and the addictions. So can it reduce all of these or just one if somebody is taking it?

 © Sebastien Bozon/AFP via Getty If we do keep seeing an effect here, it’s also important to know how quickly this happens and whether it can be sustained after you stop using a GLP-1. That’s why we have to follow people after these sorts of trials, to see if the effect can last after they stop taking the medication or if it requires people needing to stay on the drug for the effect. Gizmodo: These sort of studies are happening. But what should be the current takeaway for people with these addictions and their doctor? Is this something that could be used in the real world right now? Shah: Because they’re not approved right now, the takeaway should be that if you already have a current indication to take a GLP-1 which is for diabetes or obesity, certainly take it. If you also get an added advantage of stopping your smoking or alcohol use disorder, that is well and good because we don’t have approval for these disorders currently.

 So in other words, if somebody comes to us and says, “Hey, I want to start these medicines for smoking cessation or alcohol use disorder,” we may not be able to prescribe it because there’s no approval. But they can be part of a study which is going on in some centers for those disorders. And if somebody already is using them for diabetes or so, and in addition, they get a benefit for alcoholism, that’s great, too.      #Ozempic #Treat #Alcoholism #Heresaddiction,Alcoholism,GLP-1s,Ozempic,Q&As
© siamionau pavel via Shutterstock

There are other similar studies underway, including in the United States. Some are testing semaglutide for other kinds of substance use disorder, like opioids. Others are testing newer drugs like tirzepatide (a dual agonist that pairs GLP-1 with the hunger-related hormone GIP).

I reached out to an outside expert, Asim Shah, a professor and executive vice chair of psychiatry and behavioral sciences at Baylor College of Medicine, to talk about the emerging science surrounding GLP-1s and addiction treatment. We discussed the leading theory behind why GLP-1s can reduce addiction, his opinion of the recent Lancet trial, and what it will take for these drugs to be widely adopted as treatments for substance use disorders. The following has been lightly edited for clarity and grammar.

Ed Cara, Gizmodo: Do we have any sort of sense yet as to how or why GLP-1s seem to be working well against substance use disorders?

Asim Shah: So the craving, or pleasure, center of the brain is related to dopamine, which is a brain neurotransmitter. Whenever you crave something and you eat it or you take it, that gives you pleasure. That is the dopamine functioning in the brain. And all of this is related to the same thing, whether it’s a craving for food, craving for smoking, craving for alcohol, any drug. That’s the neurobiological mechanism of craving and pleasure, and it’s all the same mechanism.

The obesity medication Saxenda, made with liraglutide
© Mohammed_Al_Ali via Shutterstock

And incidentally, we found out that the people who were losing weight on these GLP-1s, they often also stopped smoking cigarettes and their addiction got better with alcohol. It was an incidental finding, but it’s something people are now trying to study more closely.

Gizmodo: Speaking of studies, what do you make of the newest trial published in The Lancet this month?

Shah: So this was a 26 week study, which had about 100 patients, half and half men and women both. In our world, 100 patients is a medium sized study; a larger one might usually have 300, 400, 600 patients. So this is a medium sized study, which is decent. It’s not bad. And in my opinion, it was done pretty well, not a lot of bias in the study that I saw.

Now, of course, this is not a definitive study. And you need to follow up with these patients after the weeks of study. We call these start-up studies, and they are what we base future, longer and bigger studies on. So it’s a good base, and there are other studies on the way.

Gizmodo: Broadly speaking, what are the questions that these longer and larger studies need to try answering?

Shah: So there are a couple of things.

These are different substances that people are looking at; one is alcohol, one smoking, the other is opiates. So the next studies we should be doing is to see whether GLP-1s like semaglutide can limit more than one of these addictions. Because the mechanism is the same mechanism for all the cravings and the addictions. So can it reduce all of these or just one if somebody is taking it?

Boxes of the GLP-1 medication Ozempic
© Sebastien Bozon/AFP via Getty

If we do keep seeing an effect here, it’s also important to know how quickly this happens and whether it can be sustained after you stop using a GLP-1. That’s why we have to follow people after these sorts of trials, to see if the effect can last after they stop taking the medication or if it requires people needing to stay on the drug for the effect.

Gizmodo: These sort of studies are happening. But what should be the current takeaway for people with these addictions and their doctor? Is this something that could be used in the real world right now?

Shah: Because they’re not approved right now, the takeaway should be that if you already have a current indication to take a GLP-1 which is for diabetes or obesity, certainly take it. If you also get an added advantage of stopping your smoking or alcohol use disorder, that is well and good because we don’t have approval for these disorders currently.

So in other words, if somebody comes to us and says, “Hey, I want to start these medicines for smoking cessation or alcohol use disorder,” we may not be able to prescribe it because there’s no approval. But they can be part of a study which is going on in some centers for those disorders. And if somebody already is using them for diabetes or so, and in addition, they get a benefit for alcoholism, that’s great, too.

#Ozempic #Treat #Alcoholism #Heresaddiction,Alcoholism,GLP-1s,Ozempic,Q&As">Can Ozempic Treat Alcoholism? Here’s What You Should Know
                Semaglutide (the active ingredient in Ozempic and Wegovy) and other GLP-1 medications have rapidly become some of the most popular drugs in the world. Originally developed for type 2 diabetes, GLP-1s are now better known for treating obesity. In the near future, though, these drugs could have yet another vital use as treatments for alcohol addiction and other substance use disorders. Over the past few years, a growing base of evidence has suggested that GLP-1s can tamp down people’s unhealthy urges for alcohol, cocaine, and even vices like gambling. And earlier this month, researchers in Denmark published data from the first double-blinded, randomized, and placebo-controlled trial of semaglutide for alcohol use disorder in The Lancet. Over a 26-week period, the study found that people on semaglutide consumed less alcohol than those given a placebo and experienced noticeably fewer heavy drinking days when they did drink. © siamionau pavel via Shutterstock There are other similar studies underway, including in the United States. Some are testing semaglutide for other kinds of substance use disorder, like opioids. Others are testing newer drugs like tirzepatide (a dual agonist that pairs GLP-1 with the hunger-related hormone GIP).

 I reached out to an outside expert, Asim Shah, a professor and executive vice chair of psychiatry and behavioral sciences at Baylor College of Medicine, to talk about the emerging science surrounding GLP-1s and addiction treatment. We discussed the leading theory behind why GLP-1s can reduce addiction, his opinion of the recent Lancet trial, and what it will take for these drugs to be widely adopted as treatments for substance use disorders. The following has been lightly edited for clarity and grammar.

 Ed Cara, Gizmodo: Do we have any sort of sense yet as to how or why GLP-1s seem to be working well against substance use disorders? Asim Shah: So the craving, or pleasure, center of the brain is related to dopamine, which is a brain neurotransmitter. Whenever you crave something and you eat it or you take it, that gives you pleasure. That is the dopamine functioning in the brain. And all of this is related to the same thing, whether it’s a craving for food, craving for smoking, craving for alcohol, any drug. That’s the neurobiological mechanism of craving and pleasure, and it’s all the same mechanism.

 © Mohammed_Al_Ali via Shutterstock And incidentally, we found out that the people who were losing weight on these GLP-1s, they often also stopped smoking cigarettes and their addiction got better with alcohol. It was an incidental finding, but it’s something people are now trying to study more closely. Gizmodo: Speaking of studies, what do you make of the newest trial published in The Lancet this month? Shah: So this was a 26 week study, which had about 100 patients, half and half men and women both. In our world, 100 patients is a medium sized study; a larger one might usually have 300, 400, 600 patients. So this is a medium sized study, which is decent. It’s not bad. And in my opinion, it was done pretty well, not a lot of bias in the study that I saw.

 Now, of course, this is not a definitive study. And you need to follow up with these patients after the weeks of study. We call these start-up studies, and they are what we base future, longer and bigger studies on. So it’s a good base, and there are other studies on the way. Gizmodo: Broadly speaking, what are the questions that these longer and larger studies need to try answering? Shah: So there are a couple of things. These are different substances that people are looking at; one is alcohol, one smoking, the other is opiates. So the next studies we should be doing is to see whether GLP-1s like semaglutide can limit more than one of these addictions. Because the mechanism is the same mechanism for all the cravings and the addictions. So can it reduce all of these or just one if somebody is taking it?

 © Sebastien Bozon/AFP via Getty If we do keep seeing an effect here, it’s also important to know how quickly this happens and whether it can be sustained after you stop using a GLP-1. That’s why we have to follow people after these sorts of trials, to see if the effect can last after they stop taking the medication or if it requires people needing to stay on the drug for the effect. Gizmodo: These sort of studies are happening. But what should be the current takeaway for people with these addictions and their doctor? Is this something that could be used in the real world right now? Shah: Because they’re not approved right now, the takeaway should be that if you already have a current indication to take a GLP-1 which is for diabetes or obesity, certainly take it. If you also get an added advantage of stopping your smoking or alcohol use disorder, that is well and good because we don’t have approval for these disorders currently.

 So in other words, if somebody comes to us and says, “Hey, I want to start these medicines for smoking cessation or alcohol use disorder,” we may not be able to prescribe it because there’s no approval. But they can be part of a study which is going on in some centers for those disorders. And if somebody already is using them for diabetes or so, and in addition, they get a benefit for alcoholism, that’s great, too.      #Ozempic #Treat #Alcoholism #Heresaddiction,Alcoholism,GLP-1s,Ozempic,Q&As

that GLP-1s can tamp down people’s unhealthy urges for alcohol, cocaine, and even vices like gambling. And earlier this month, researchers in Denmark published data from the first double-blinded, randomized, and placebo-controlled trial of semaglutide for alcohol use disorder in The Lancet. Over a 26-week period, the study found that people on semaglutide consumed less alcohol than those given a placebo and experienced noticeably fewer heavy drinking days when they did drink.

Can Ozempic Treat Alcoholism? Here’s What You Should Know
                Semaglutide (the active ingredient in Ozempic and Wegovy) and other GLP-1 medications have rapidly become some of the most popular drugs in the world. Originally developed for type 2 diabetes, GLP-1s are now better known for treating obesity. In the near future, though, these drugs could have yet another vital use as treatments for alcohol addiction and other substance use disorders. Over the past few years, a growing base of evidence has suggested that GLP-1s can tamp down people’s unhealthy urges for alcohol, cocaine, and even vices like gambling. And earlier this month, researchers in Denmark published data from the first double-blinded, randomized, and placebo-controlled trial of semaglutide for alcohol use disorder in The Lancet. Over a 26-week period, the study found that people on semaglutide consumed less alcohol than those given a placebo and experienced noticeably fewer heavy drinking days when they did drink. © siamionau pavel via Shutterstock There are other similar studies underway, including in the United States. Some are testing semaglutide for other kinds of substance use disorder, like opioids. Others are testing newer drugs like tirzepatide (a dual agonist that pairs GLP-1 with the hunger-related hormone GIP).

 I reached out to an outside expert, Asim Shah, a professor and executive vice chair of psychiatry and behavioral sciences at Baylor College of Medicine, to talk about the emerging science surrounding GLP-1s and addiction treatment. We discussed the leading theory behind why GLP-1s can reduce addiction, his opinion of the recent Lancet trial, and what it will take for these drugs to be widely adopted as treatments for substance use disorders. The following has been lightly edited for clarity and grammar.

 Ed Cara, Gizmodo: Do we have any sort of sense yet as to how or why GLP-1s seem to be working well against substance use disorders? Asim Shah: So the craving, or pleasure, center of the brain is related to dopamine, which is a brain neurotransmitter. Whenever you crave something and you eat it or you take it, that gives you pleasure. That is the dopamine functioning in the brain. And all of this is related to the same thing, whether it’s a craving for food, craving for smoking, craving for alcohol, any drug. That’s the neurobiological mechanism of craving and pleasure, and it’s all the same mechanism.

 © Mohammed_Al_Ali via Shutterstock And incidentally, we found out that the people who were losing weight on these GLP-1s, they often also stopped smoking cigarettes and their addiction got better with alcohol. It was an incidental finding, but it’s something people are now trying to study more closely. Gizmodo: Speaking of studies, what do you make of the newest trial published in The Lancet this month? Shah: So this was a 26 week study, which had about 100 patients, half and half men and women both. In our world, 100 patients is a medium sized study; a larger one might usually have 300, 400, 600 patients. So this is a medium sized study, which is decent. It’s not bad. And in my opinion, it was done pretty well, not a lot of bias in the study that I saw.

 Now, of course, this is not a definitive study. And you need to follow up with these patients after the weeks of study. We call these start-up studies, and they are what we base future, longer and bigger studies on. So it’s a good base, and there are other studies on the way. Gizmodo: Broadly speaking, what are the questions that these longer and larger studies need to try answering? Shah: So there are a couple of things. These are different substances that people are looking at; one is alcohol, one smoking, the other is opiates. So the next studies we should be doing is to see whether GLP-1s like semaglutide can limit more than one of these addictions. Because the mechanism is the same mechanism for all the cravings and the addictions. So can it reduce all of these or just one if somebody is taking it?

 © Sebastien Bozon/AFP via Getty If we do keep seeing an effect here, it’s also important to know how quickly this happens and whether it can be sustained after you stop using a GLP-1. That’s why we have to follow people after these sorts of trials, to see if the effect can last after they stop taking the medication or if it requires people needing to stay on the drug for the effect. Gizmodo: These sort of studies are happening. But what should be the current takeaway for people with these addictions and their doctor? Is this something that could be used in the real world right now? Shah: Because they’re not approved right now, the takeaway should be that if you already have a current indication to take a GLP-1 which is for diabetes or obesity, certainly take it. If you also get an added advantage of stopping your smoking or alcohol use disorder, that is well and good because we don’t have approval for these disorders currently.

 So in other words, if somebody comes to us and says, “Hey, I want to start these medicines for smoking cessation or alcohol use disorder,” we may not be able to prescribe it because there’s no approval. But they can be part of a study which is going on in some centers for those disorders. And if somebody already is using them for diabetes or so, and in addition, they get a benefit for alcoholism, that’s great, too.      #Ozempic #Treat #Alcoholism #Heresaddiction,Alcoholism,GLP-1s,Ozempic,Q&As
© siamionau pavel via Shutterstock

There are other similar studies underway, including in the United States. Some are testing semaglutide for other kinds of substance use disorder, like opioids. Others are testing newer drugs like tirzepatide (a dual agonist that pairs GLP-1 with the hunger-related hormone GIP).

I reached out to an outside expert, Asim Shah, a professor and executive vice chair of psychiatry and behavioral sciences at Baylor College of Medicine, to talk about the emerging science surrounding GLP-1s and addiction treatment. We discussed the leading theory behind why GLP-1s can reduce addiction, his opinion of the recent Lancet trial, and what it will take for these drugs to be widely adopted as treatments for substance use disorders. The following has been lightly edited for clarity and grammar.

Ed Cara, Gizmodo: Do we have any sort of sense yet as to how or why GLP-1s seem to be working well against substance use disorders?

Asim Shah: So the craving, or pleasure, center of the brain is related to dopamine, which is a brain neurotransmitter. Whenever you crave something and you eat it or you take it, that gives you pleasure. That is the dopamine functioning in the brain. And all of this is related to the same thing, whether it’s a craving for food, craving for smoking, craving for alcohol, any drug. That’s the neurobiological mechanism of craving and pleasure, and it’s all the same mechanism.

The obesity medication Saxenda, made with liraglutide
© Mohammed_Al_Ali via Shutterstock

And incidentally, we found out that the people who were losing weight on these GLP-1s, they often also stopped smoking cigarettes and their addiction got better with alcohol. It was an incidental finding, but it’s something people are now trying to study more closely.

Gizmodo: Speaking of studies, what do you make of the newest trial published in The Lancet this month?

Shah: So this was a 26 week study, which had about 100 patients, half and half men and women both. In our world, 100 patients is a medium sized study; a larger one might usually have 300, 400, 600 patients. So this is a medium sized study, which is decent. It’s not bad. And in my opinion, it was done pretty well, not a lot of bias in the study that I saw.

Now, of course, this is not a definitive study. And you need to follow up with these patients after the weeks of study. We call these start-up studies, and they are what we base future, longer and bigger studies on. So it’s a good base, and there are other studies on the way.

Gizmodo: Broadly speaking, what are the questions that these longer and larger studies need to try answering?

Shah: So there are a couple of things.

These are different substances that people are looking at; one is alcohol, one smoking, the other is opiates. So the next studies we should be doing is to see whether GLP-1s like semaglutide can limit more than one of these addictions. Because the mechanism is the same mechanism for all the cravings and the addictions. So can it reduce all of these or just one if somebody is taking it?

Boxes of the GLP-1 medication Ozempic
© Sebastien Bozon/AFP via Getty

If we do keep seeing an effect here, it’s also important to know how quickly this happens and whether it can be sustained after you stop using a GLP-1. That’s why we have to follow people after these sorts of trials, to see if the effect can last after they stop taking the medication or if it requires people needing to stay on the drug for the effect.

Gizmodo: These sort of studies are happening. But what should be the current takeaway for people with these addictions and their doctor? Is this something that could be used in the real world right now?

Shah: Because they’re not approved right now, the takeaway should be that if you already have a current indication to take a GLP-1 which is for diabetes or obesity, certainly take it. If you also get an added advantage of stopping your smoking or alcohol use disorder, that is well and good because we don’t have approval for these disorders currently.

So in other words, if somebody comes to us and says, “Hey, I want to start these medicines for smoking cessation or alcohol use disorder,” we may not be able to prescribe it because there’s no approval. But they can be part of a study which is going on in some centers for those disorders. And if somebody already is using them for diabetes or so, and in addition, they get a benefit for alcoholism, that’s great, too.

#Ozempic #Treat #Alcoholism #Heresaddiction,Alcoholism,GLP-1s,Ozempic,Q&As">Can Ozempic Treat Alcoholism? Here’s What You Should Know

Semaglutide (the active ingredient in Ozempic and Wegovy) and other GLP-1 medications have rapidly become some of the most popular drugs in the world. Originally developed for type 2 diabetes, GLP-1s are now better known for treating obesity. In the near future, though, these drugs could have yet another vital use as treatments for alcohol addiction and other substance use disorders.

Over the past few years, a growing base of evidence has suggested that GLP-1s can tamp down people’s unhealthy urges for alcohol, cocaine, and even vices like gambling. And earlier this month, researchers in Denmark published data from the first double-blinded, randomized, and placebo-controlled trial of semaglutide for alcohol use disorder in The Lancet. Over a 26-week period, the study found that people on semaglutide consumed less alcohol than those given a placebo and experienced noticeably fewer heavy drinking days when they did drink.

Can Ozempic Treat Alcoholism? Here’s What You Should Know
                Semaglutide (the active ingredient in Ozempic and Wegovy) and other GLP-1 medications have rapidly become some of the most popular drugs in the world. Originally developed for type 2 diabetes, GLP-1s are now better known for treating obesity. In the near future, though, these drugs could have yet another vital use as treatments for alcohol addiction and other substance use disorders. Over the past few years, a growing base of evidence has suggested that GLP-1s can tamp down people’s unhealthy urges for alcohol, cocaine, and even vices like gambling. And earlier this month, researchers in Denmark published data from the first double-blinded, randomized, and placebo-controlled trial of semaglutide for alcohol use disorder in The Lancet. Over a 26-week period, the study found that people on semaglutide consumed less alcohol than those given a placebo and experienced noticeably fewer heavy drinking days when they did drink. © siamionau pavel via Shutterstock There are other similar studies underway, including in the United States. Some are testing semaglutide for other kinds of substance use disorder, like opioids. Others are testing newer drugs like tirzepatide (a dual agonist that pairs GLP-1 with the hunger-related hormone GIP).

 I reached out to an outside expert, Asim Shah, a professor and executive vice chair of psychiatry and behavioral sciences at Baylor College of Medicine, to talk about the emerging science surrounding GLP-1s and addiction treatment. We discussed the leading theory behind why GLP-1s can reduce addiction, his opinion of the recent Lancet trial, and what it will take for these drugs to be widely adopted as treatments for substance use disorders. The following has been lightly edited for clarity and grammar.

 Ed Cara, Gizmodo: Do we have any sort of sense yet as to how or why GLP-1s seem to be working well against substance use disorders? Asim Shah: So the craving, or pleasure, center of the brain is related to dopamine, which is a brain neurotransmitter. Whenever you crave something and you eat it or you take it, that gives you pleasure. That is the dopamine functioning in the brain. And all of this is related to the same thing, whether it’s a craving for food, craving for smoking, craving for alcohol, any drug. That’s the neurobiological mechanism of craving and pleasure, and it’s all the same mechanism.

 © Mohammed_Al_Ali via Shutterstock And incidentally, we found out that the people who were losing weight on these GLP-1s, they often also stopped smoking cigarettes and their addiction got better with alcohol. It was an incidental finding, but it’s something people are now trying to study more closely. Gizmodo: Speaking of studies, what do you make of the newest trial published in The Lancet this month? Shah: So this was a 26 week study, which had about 100 patients, half and half men and women both. In our world, 100 patients is a medium sized study; a larger one might usually have 300, 400, 600 patients. So this is a medium sized study, which is decent. It’s not bad. And in my opinion, it was done pretty well, not a lot of bias in the study that I saw.

 Now, of course, this is not a definitive study. And you need to follow up with these patients after the weeks of study. We call these start-up studies, and they are what we base future, longer and bigger studies on. So it’s a good base, and there are other studies on the way. Gizmodo: Broadly speaking, what are the questions that these longer and larger studies need to try answering? Shah: So there are a couple of things. These are different substances that people are looking at; one is alcohol, one smoking, the other is opiates. So the next studies we should be doing is to see whether GLP-1s like semaglutide can limit more than one of these addictions. Because the mechanism is the same mechanism for all the cravings and the addictions. So can it reduce all of these or just one if somebody is taking it?

 © Sebastien Bozon/AFP via Getty If we do keep seeing an effect here, it’s also important to know how quickly this happens and whether it can be sustained after you stop using a GLP-1. That’s why we have to follow people after these sorts of trials, to see if the effect can last after they stop taking the medication or if it requires people needing to stay on the drug for the effect. Gizmodo: These sort of studies are happening. But what should be the current takeaway for people with these addictions and their doctor? Is this something that could be used in the real world right now? Shah: Because they’re not approved right now, the takeaway should be that if you already have a current indication to take a GLP-1 which is for diabetes or obesity, certainly take it. If you also get an added advantage of stopping your smoking or alcohol use disorder, that is well and good because we don’t have approval for these disorders currently.

 So in other words, if somebody comes to us and says, “Hey, I want to start these medicines for smoking cessation or alcohol use disorder,” we may not be able to prescribe it because there’s no approval. But they can be part of a study which is going on in some centers for those disorders. And if somebody already is using them for diabetes or so, and in addition, they get a benefit for alcoholism, that’s great, too.      #Ozempic #Treat #Alcoholism #Heresaddiction,Alcoholism,GLP-1s,Ozempic,Q&As
© siamionau pavel via Shutterstock

There are other similar studies underway, including in the United States. Some are testing semaglutide for other kinds of substance use disorder, like opioids. Others are testing newer drugs like tirzepatide (a dual agonist that pairs GLP-1 with the hunger-related hormone GIP).

I reached out to an outside expert, Asim Shah, a professor and executive vice chair of psychiatry and behavioral sciences at Baylor College of Medicine, to talk about the emerging science surrounding GLP-1s and addiction treatment. We discussed the leading theory behind why GLP-1s can reduce addiction, his opinion of the recent Lancet trial, and what it will take for these drugs to be widely adopted as treatments for substance use disorders. The following has been lightly edited for clarity and grammar.

Ed Cara, Gizmodo: Do we have any sort of sense yet as to how or why GLP-1s seem to be working well against substance use disorders?

Asim Shah: So the craving, or pleasure, center of the brain is related to dopamine, which is a brain neurotransmitter. Whenever you crave something and you eat it or you take it, that gives you pleasure. That is the dopamine functioning in the brain. And all of this is related to the same thing, whether it’s a craving for food, craving for smoking, craving for alcohol, any drug. That’s the neurobiological mechanism of craving and pleasure, and it’s all the same mechanism.

The obesity medication Saxenda, made with liraglutide
© Mohammed_Al_Ali via Shutterstock

And incidentally, we found out that the people who were losing weight on these GLP-1s, they often also stopped smoking cigarettes and their addiction got better with alcohol. It was an incidental finding, but it’s something people are now trying to study more closely.

Gizmodo: Speaking of studies, what do you make of the newest trial published in The Lancet this month?

Shah: So this was a 26 week study, which had about 100 patients, half and half men and women both. In our world, 100 patients is a medium sized study; a larger one might usually have 300, 400, 600 patients. So this is a medium sized study, which is decent. It’s not bad. And in my opinion, it was done pretty well, not a lot of bias in the study that I saw.

Now, of course, this is not a definitive study. And you need to follow up with these patients after the weeks of study. We call these start-up studies, and they are what we base future, longer and bigger studies on. So it’s a good base, and there are other studies on the way.

Gizmodo: Broadly speaking, what are the questions that these longer and larger studies need to try answering?

Shah: So there are a couple of things.

These are different substances that people are looking at; one is alcohol, one smoking, the other is opiates. So the next studies we should be doing is to see whether GLP-1s like semaglutide can limit more than one of these addictions. Because the mechanism is the same mechanism for all the cravings and the addictions. So can it reduce all of these or just one if somebody is taking it?

Boxes of the GLP-1 medication Ozempic
© Sebastien Bozon/AFP via Getty

If we do keep seeing an effect here, it’s also important to know how quickly this happens and whether it can be sustained after you stop using a GLP-1. That’s why we have to follow people after these sorts of trials, to see if the effect can last after they stop taking the medication or if it requires people needing to stay on the drug for the effect.

Gizmodo: These sort of studies are happening. But what should be the current takeaway for people with these addictions and their doctor? Is this something that could be used in the real world right now?

Shah: Because they’re not approved right now, the takeaway should be that if you already have a current indication to take a GLP-1 which is for diabetes or obesity, certainly take it. If you also get an added advantage of stopping your smoking or alcohol use disorder, that is well and good because we don’t have approval for these disorders currently.

So in other words, if somebody comes to us and says, “Hey, I want to start these medicines for smoking cessation or alcohol use disorder,” we may not be able to prescribe it because there’s no approval. But they can be part of a study which is going on in some centers for those disorders. And if somebody already is using them for diabetes or so, and in addition, they get a benefit for alcoholism, that’s great, too.

#Ozempic #Treat #Alcoholism #Heresaddiction,Alcoholism,GLP-1s,Ozempic,Q&As

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